Skip to main content

Table 1 Characteristics of the eligible studies

From: The efficacy and safety of induction chemotherapy combined with concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in nasopharyngeal carcinoma patients: a systematic review and meta-analysis

StudyYearInclusion periodRegisterRegion/ CountryPhaseGroupNo.patientsNo.maleMean Age (range, year)StageAJCCMedian follow-up (years)Jadad score
Fountzilas [8]20122003–2008ACTRN
12609000730202
EuropeIIIC + CCRT
CCRT
72
69
55
48
49 (19–82)
51 (15–79)
IIb-IVb6th4.64
Tan [9]20152004–2012CDR0000657121SingaporeII/IIIIC + CCRT
CCRT
86
86
71
63
49 (42–55)
52 (44–57)
III-IVb5th3.4
3.2
3
Sun [10]/
Li [11]
2016/20192011–2013NCT01245959ChinaIIIIC + CCRT
CCRT
241
239
193
174
42 (36–49)
44 (39–50)
III-IVb7th63
Cao [12]/
Yang [13]
2017/20192008–2015NCT00705627ChinaIIIIC + CCRT
CCRT
238
238
173
190
44 (19–65)42 (21–66)III-IVb6th6.93
Frikha [14]20182009–2012NCT00828386France/ TunisiaIIIIC + CCRT
CCRT
42
41
28
32
46
48
T2b, T3, T4 and/or N1-N3, M0NR3.63
Hong [15]20182003–2009NCT00201396ChinaIIIIC + CCRT
CCRT
239
240
176
179
45 (15–69)
47 (19–70)
IVa-IVb5th63
Zhang [16]20192013–2016NCT01872962ChinaIIIIC + CCRT
CCRT
242
238
182
164
46 (18–64)
45 (20–64)
III-IVb7th3.63
  1. IC induction chemotherapy; CCRT concurrent chemoradiotherapy; AJCC American Joint Cancer Committee; NR not reported