Table 4 Univariable associations (Gray’s test) of LC and dosimetric/treatment variables
From: Stereotactic robotic body radiotherapy for patients with oligorecurrent pulmonary metastases
Endpoint | Local control | |
|---|---|---|
Dosimetric variables | Hazard ratio (95% CI) | p value |
Number of fractions (> 3 vs 3) | 1.93 (0.89–4.19) | 0.097 |
BED prescription (> 120 Gy vs < 120 Gy) | 0.25 (0.11–0.56) | < 0.001 |
Tracking (Synchrony vs XSight L./Sp.) | 1.39 (0.60–3.24) | 0.45 |
GTV volume (> 10 cc vs < 10 cc) | 3.46 (1.55–7.69) | 0.0021 |
CTV volume (> 20 cc vs < 20 cc) | 2.14 (0.97–4.75) | 0.063 |
PTV volume (> 25 cc vs < 25 cc) | 2.00 (0.91–4.39) | 0.085 |
GTV mean dose (> 70 Gy vs < 70 Gy) | 0.22 (0.079–0.63) | 0.0025 |
CTV mean dose (> 65 Gy vs < 65 Gy) | 0.33 (0.15–0.73) | 0.0052 |
PTV mean dose (> 65 Gy vs < 65 Gy) | 0.33 (0.15–0.73) | 0.0052 |
GTV D95 (> 60 Gy vs < 60 Gy) | 0.36 (0.16–0.79) | 0.0096 |
CTV D95 (> 60 Gy vs < 60 Gy) | 0.40 (0.18–0.88) | 0.022 |
PTV D95 (> 60 Gy vs < 60 Gy) | 0.31 (0.13–0.76) | 0.0077 |
GTV V160BED10 (> 95% vs < 95%) | 0.39 (0.18–0.87) | 0.021 |
CTV V160BED10 (> 95% vs < 95%) | 0.44 (0.20–0.97) | 0.041 |
PTV V160BED10 (> 95% vs < 95%) | 0.47 (0.21–1.03) | 0.058 |
GTV D2% (> 65 Gy vs < 65 Gy) | 0.33 (0.15–0.72) | 0.0055 |
GTV D2%BED10 (> 165 Gy vs < 165 Gy) | 0.32 (0.15–0.70) | 0.0044 |