Different regulation of PARP1, PARP2, PARP3 and TRPM2 genes expression in acute myeloid leukemia cells

BMC Cancer

Table 2 Mean PARP1, PARP2, PARP3, and TRPM2 gene expression (2^-ΔΔCt ± SE) in tested groups

Mean gene expression in tested group
Gene	Group	N	Mean 2^-ddCT	SE	p-value
Gene	Group	N	Mean 2^-ddCT	SE	AML	PBMC	PBSC	BM
*PARP1*	AML	14	3.572	1.099		0.156	0.001^a	0.455
	PBMC	21	1.185	0.146	0.156		0.968	0.899
	PBSC	39	0.615	0.054	0.001^a	0.968		0.379
	BM	10	1.243	0.121	0.455	0.899	0.379
*PARP2*	AML	14	7.463	2.709		0.163	0.003^a	0.224
	PBMC	21	0.923	0.110	0.163		0.992	0.988
	PBSC	39	0.709	0.086	0.003^a	0.992		0.799
	BM	10	1.349	0.271	0.224	0.988	0.799
*PARP3*	AML	14	1.684	0.394		0.858	0.700	0.973
	PBMC	21	0.888	0.101	0.858		1.000	0.989
	PBSC	39	0.808	0.083	0.700	1.000		0.990
	BM	10	0.984	0.126	0.973	0.989	0.990
*TRPM2*	AML	14	4.191	2.317		0.997	0.841	0.016^a
	PBMC	21	0.549	0.178	0.997		0.828	0.025^a
	PBSC	39	1.934	0.612	0.841	0.828		0.033^a
	BM	10	10.392	2.039	0.016^a	0.025^a	0.033^a

ISSN: 1471-2407