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Fig. 4 | BMC Cancer

Fig. 4

From: Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer

Fig. 4

Activity of CB-839 in 3D spheroid versus 2D monolayer cell cultures. Images of MDA-MB-231 (a), SUM159PT (b) and Hs578T (c) 3D spheroid cell cultures captured on day 4 and 8 (scale bar = 0.5 mm). Thymidine incorporation in MDA-MB-231 (d), SUM159PT (e) and Hs578T (f) 3D spheroid cultures and 2D monolayer cultures following 4 days treatment with CB-839 (mean ± SEM, n = 4–6)

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BMC Cancer

ISSN: 1471-2407

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