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Table 1 Cohort characteristics

From: Inferring the role of the microbiome on survival in patients treated with immune checkpoint inhibitors: causal modeling, timing, and classes of concomitant medications

Overall n

689

BMI (mean (sd))

27.76 (6.62)

Age (mean (sd))

62.27 (13.21)

Sex = Male (%)

402 (58.3)

ECOG (%)

 0

185 (31.0)

 1

272 (45.6)

 2

113 (19.0)

  > 2

26 (4.4)

CCI = 0–1 (%)

458 (66.7)

Cancer (%)

 Bladder Cancer

32 (4.9)

 Head and Neck Carcinoma

42 (6.5)

 Melanoma

184 (28.4)

 Non-Small Cell Lung Cancer

152 (23.5)

 Renal Cell Carcinoma

65 (10.0)

 Sarcoma

21 (3.2)

 Other

152 (23.5)

Staging (%)

 1

1 (0.2)

 2

4 (0.7)

 3

44 (7.2)

 4

547 (90.0)

 Unknown

12 (2.0)

Immune Checkpoint Inhibitors (%)

 Atezolizumab

22 (3.2)

 Durvalumab

12 (1.7)

 Durva + Tremelimumab

6 (0.9)

 Ipilimumab

126 (18.3)

 Nivolumab

364 (52.8)

 Nivolumab + Ipilimumab

37 (5.4)

 Pembrolizumab

104 (15.1)

 Tremelimumab

3 (0.4)

 Other

15 (2.2)

ATB within 28 days of ICI (%)

241 (35.0)

CS within 28 days of ICI (%)

273 (39.6)