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Table 4 Bivariate and multivariate association between change in the initial cancer treatment plan and comprehensive geriatric assessment

From: Impact of the comprehensive geriatric assessment on treatment decision in geriatric oncology

Characteristics

Bivariate OR (95% CI)

p

Multivariate OR (95% CI)

p

Age (years)

1.06 (1.01–1.11)

0.014

–

 

Gender (female)

1.27 (0.74–2.17)

0.386

–

 

Living conditions (Live alone)

1.07 (0.60–1.90)

0.827

–

 

Marital status

  

–

 

 Married (vs widowed, single or divorced)

0.85 (0.49–1.46)

0.553

  

Education (n = 438)

  

–

 

 Middle/ High School/ College (vs no education or elementary school)

0.71 (0.41–1.24)

0.235

  

Charlson Comorbidity Index

1.06 (0.99–1.26)

0.466

–

 

Number of drug (≥ 5)

1.77 (0.98–3.19)

0.057

–

 

MMSE (≤24)

3.53 (1.98–6.29)

< 0.001

2.15 (1.13–4.12)

0.020

MNA (n = 429)

 MNA ≥ 24

1

 

1

 

 MNA (17–23.5)

2.45 (1.22–4.93)

0.012

1.44 (0.62–3.34)

0.391

 MNA < 17

11.08 (4.68–26.22)

< 0.001

3.33 (1.18–9.37)

0.023

ADL (≤5)

4.64 (2.65–8.12)

< 0.001

–

 

IADL (≤7)

7.12 ((2.17–23.30)

0.001

–

 

SPPB

 10–12 (high performance)

1

 

1

 

 7–9 (medium performance)

1.91 (0.69–5.27)

0.210

1.50 (0.45–4.98)

0.511

  ≤ 6 (low performance)

9.56 (3.90–23.40)

< 0.001

4.55 (1.43–14.46)

0.10

Gait speed (< 1 m/s)

3.22 (1.34–7.75)

0.009

  

Fried’s criteria

  

–

 

 Robust (0 criteria)

1

   

 Pre-frail (1–2 criteria)

0.39 (0.09–1.65)

0.200

  

 Frail (≥ 3 criteria)

3.21 (0.94–11.01)

0.063

  

Hearing impairment

0.89 (0.49–1.60)

0.694

–

 

Visual impairment

2.01 (1.06–3.83)

0.031

–

 
  1. OR Odds Ratio, MMSE Mini Mental State Examination, MNA Mini-Nutritional Assessment, ADL Activities of Daily Living, IADL Instrumental Activities of Daily Living, SPPB Short Physical Performance Battery, HHIES Hearing Handicap Inventory fort the Elderly – Screening