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Table 4 Bivariate and multivariate association between change in the initial cancer treatment plan and comprehensive geriatric assessment

From: Impact of the comprehensive geriatric assessment on treatment decision in geriatric oncology

Characteristics Bivariate OR (95% CI) p Multivariate OR (95% CI) p
Age (years) 1.06 (1.01–1.11) 0.014  
Gender (female) 1.27 (0.74–2.17) 0.386  
Living conditions (Live alone) 1.07 (0.60–1.90) 0.827  
Marital status    
 Married (vs widowed, single or divorced) 0.85 (0.49–1.46) 0.553   
Education (n = 438)    
 Middle/ High School/ College (vs no education or elementary school) 0.71 (0.41–1.24) 0.235   
Charlson Comorbidity Index 1.06 (0.99–1.26) 0.466  
Number of drug (≥ 5) 1.77 (0.98–3.19) 0.057  
MMSE (≤24) 3.53 (1.98–6.29) < 0.001 2.15 (1.13–4.12) 0.020
MNA (n = 429)
 MNA ≥ 24 1   1  
 MNA (17–23.5) 2.45 (1.22–4.93) 0.012 1.44 (0.62–3.34) 0.391
 MNA < 17 11.08 (4.68–26.22) < 0.001 3.33 (1.18–9.37) 0.023
ADL (≤5) 4.64 (2.65–8.12) < 0.001  
IADL (≤7) 7.12 ((2.17–23.30) 0.001  
SPPB
 10–12 (high performance) 1   1  
 7–9 (medium performance) 1.91 (0.69–5.27) 0.210 1.50 (0.45–4.98) 0.511
  ≤ 6 (low performance) 9.56 (3.90–23.40) < 0.001 4.55 (1.43–14.46) 0.10
Gait speed (< 1 m/s) 3.22 (1.34–7.75) 0.009   
Fried’s criteria    
 Robust (0 criteria) 1    
 Pre-frail (1–2 criteria) 0.39 (0.09–1.65) 0.200   
 Frail (≥ 3 criteria) 3.21 (0.94–11.01) 0.063   
Hearing impairment 0.89 (0.49–1.60) 0.694  
Visual impairment 2.01 (1.06–3.83) 0.031  
  1. OR Odds Ratio, MMSE Mini Mental State Examination, MNA Mini-Nutritional Assessment, ADL Activities of Daily Living, IADL Instrumental Activities of Daily Living, SPPB Short Physical Performance Battery, HHIES Hearing Handicap Inventory fort the Elderly – Screening