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Table 1 Correlations between surrogate endpoints and OS

From: A meta-analytic evaluation of the correlation between event-free survival and overall survival in randomized controlled trials of newly diagnosed Ewing sarcoma

Surrogate endpointR2 (95% CI)ρ (95% CI)P-value
EFS0.747 (0.513–0.981)0.683 (0.035–0.927)0.042
1-year EFS0.348 (0.00–0.759)0.450 (−0.305–0.858)0.22
3-year EFS0.765 (0.545–0.985)0.717 (0.10–0.936)0.030
5-year EFS0.695 (0.423–0.967)0.767 (0.209–0.948)0.016
1-year OS0.089 (0.00–0.408)0.214 (−0.642–0.833)0.64
3-year OS0.831 (0.650–1.00)0.929 (0.584–0.990)0.0025
5-year OS0.809 (0.625–0.993)0.767 (0.209–0.948)0.016
  1. Abbreviations: CI confidence interval; OS overall survival; EFS event-free survival