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Table 3 Chemotherapeutic Efficacy

From: Clinical utility of polyethylene glycol conjugated granulocyte colony-stimulating factor (PEG-G-CSF) for preventing severe neutropenia in metastatic colorectal cancer patients treated with FOLFOXIRI plus bevacizumab: a single-center retrospective study

Characteristics

Total (n = 26) No. of patients (%)

With Prophylactic PEG-G-CSF (n = 9)

Without Prophylactic PEG-G-CSF (n = 11)

No use of PEG-G-CSF (n = 6)

Number of cycles

 Median

6.5

8

6

7

 Range

1.0–14.0

3.0–10.0

5.0–14.0

1.0–11.0

Dose reduction

 Yes

10 (38.5)

2 (22.2)

5 (45.4)

3 (50.0)

 No

16 (61.5)

7 (77.8)

6 (54.6)

3 (50.0)

ORR

 Partial response

17 (65.3)

3 (33.3)

10 (90.9)

4 (66.7)

 Stable disease

5 (19.2)

2 (22.3)

1 (9.1)

2 (33.3)

 Progressive disease

1 (3.8)

1 (11.1)

0 (0)

0 (0)

 Not evaluate

3 (11.5)

3 (33.3)

0 (0)

0 (0)

Conversion surgery

 Yes

7 (26.9)

2 (22.2)

5 (45.4)

2 (33.3)

 No

19 (73.1)

7 (77.8)

6 (54.6)

4 (66.7)

Early Tumor Response

 Yes

13 (50.0)

1 (11.1)

9 (81.8)

3 (50.0)

 No

10 (38.4)

5 (55.6)

2 (18.2)

3 (50.0)

 Not evaluated

3 (11.6)

3 (33.3)

0 (0)

0 (0)