Biomarker roles identification of miR-106 family for predicting the risk and poor survival of colorectal cancer

BMC Cancer

Table 1 The main features of the included studies for miR-106 family in the diagnosis of CRC

First author	Year	Country	Ethnicity	Case			Control					Sample source	Methods	miRNA	AUC	Sensitivity	Specificity
First author	Year	Country	Ethnicity	M	F	N	Age	M	F	N	Age	Sample source	Methods	miRNA	AUC	Sensitivity	Specificity
Kuriyama et al. [37]	2012	Japan	Asian	NA	NA	138	NA	NA	NA	126	NA	Feces	RT-PCR	miR-106a	0.826	37.70%	99.20%
Luo et al. [21]	2013	Germany	European	45	35	80	68	60	84	144	62	Plasma	RT-PCR	miR-106b	0.565	19.00%	95.00%
Koga et al. [20]	2013	Japan	Asian	69	48	117	65	66	41	107	60	Feces	RT-PCR	miR-106a	NA	34.20%	97.20%
Chen et al. [22]	2015	China	Asian	60	40	100	60	44	35	79	60	Plasma	RT-PCR	miR-106a	0.605	74.00%	44.40%
Li et al. [23]	2015	China	Asian	113	62	175	57	51	79	130	54	Serum	RT-PCR	miR-106a	0.813	69.00%	83.00%
He et al. [24]	2017	China	Asian	23	19	42	63	24	18	42	60	Plasma	RT-PCR	miR-106a	0.858	74.20%	86.10%

ISSN: 1471-2407