Table 3 Univariate and multivariate logistic regression analysis
Variables | Univariate | Multivariate | ||
|---|---|---|---|---|
OR (95% CI) | p-value | OR (95% CI) | p-value | |
Gender | ||||
 Male | Reference | – | ||
 Female | 0.7 (0.5–1) | 0.108 | – | – |
Age (years) | ||||
  ≤ 50 | Reference | – | ||
  > 50 | 0.8 (0.5–1.2) | 0.318 | – | – |
All drugs prescribed | ||||
  ≤ 7 | Reference | Reference | ||
  > 7 | 3.6 (2.5–5.3) | 0.0001 | 3.5 (2.2–5.5) | 0.0001 |
Anticancer drugs | ||||
  ≤ 2 | Reference | Reference | ||
  ≥ 3 | 4.7 (3–7.4) | 0.0001 | 3.6 (2.1–6.2) | 0.0001 |
Supportive care drugs | ||||
  ≤ 3 | Reference | Reference | ||
  > 3 | 1.9 (1.3–2.9) | 0.001 | 0.6 (0.3–1.2) | 0.161 |
Hospitalization status | ||||
 Ambulatory | Reference | Reference | ||
 Hospitalized | 1.8 (1.2–2.6) | 0.004 | 1.3 (0.8–2) | 0.327 |
Cancer type | ||||
 Hematological malignancy | Reference | Reference | ||
 Solid malignancy | 0.4 (0.3–0.6) | 0.0001 | 0.7 (0.4–1.1) | 0.173 |
Metastasis | ||||
 Present | Reference | – | ||
 Absent | 1.5 (0.9–2.4) | 0.07 | – | – |
Treatment type | ||||
 Cytotoxic agents | Reference | Reference | ||
 Combination drugsa | 2.1 (1.3–3.4) | 0.003 | 0.7 (0.4–1.3) | 0.343 |
Treatment intent | ||||
 Curative | Reference | – | ||
 Palliative | 1.6 (0.8–3.3) | 0.218 | – | – |