Fig. 2

Kaplan-Meier curves for overall survival. The median overall survival was 18.0 months (95% confidence interval [CI], 16.1–19.9) and 11.9 months (95% CI, 8.8–15.0) for the CB and CA groups, respectively. Significant differences were detected in overall survival between groups. *The hazard ratio was calculated using a Cox proportional hazards model, with the age, the site of primary tumour, the number of metastatic sites, and the performance status used as covariates and CB/CA therapy as the time-dependent factor. With respect to the overall survival, the results of a log-rank test reported p = 0.002