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Table 4 Results of the multivariable regression analyses for the WHOQOL-BREF (p < 0.05)

From: The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

Independent variablesNBSEβP-valueCorrected P-valuea95% CI for BR2
 General facet
 Age117−0.0410.015−0.2320.0060.024−0.070, − 0.0120.402
 CES-D −0.1330.021−0.625< 0.001< 0.001−0.175, − 0.091 
Physical health
 ECOG: 0 to 1 versus 2 or higher117−2.7470.751−0.262< 0.001< 0.001−4.234, −1.2590.517
 CES-D −0.2210.035−0.542< 0.001< 0.001−0.291, − 0.151 
 NEO-FFI conscientiousness 0.1110.0450.2010.0160.0430.021, 0.200 
 Psychological health
 CES-D117−0.1630.025−0.534< 0.0010.000−0.213, − 0.1130.554
 Social relationships
 Gender1191.1070.4670.2220.0200.0800.181, 2.0320.204
 Partner status: no partner versus having a partner 1.4280.5880.2160.0170.0800.262,
2.594
 
 Environment
 CES-D116−0.0630.028−0.2240.0260.091−0.118,
− 0.008
0.375
 STAI Trait −0.1630.049−0.3920.0010.007−0.259,
− 0.066
 
  1. aBenjamini-Hochberg method was used to correct P-values
  2. Abbreviations: WHOQOL-BREF World Health Organization Quality of Life-BREF questionnaire, N number of patients, B unstandardized beta, SE standard error, β standardized beta, CI confidence interval, R2 explained varriance, CES-D Center for Epidemiologic Studies Depression Scale, ECOG Eastern Cooperative Oncology Group, NEO-FFI Neuroticism-Extraversion-Openness-Five Factor Inventory questionnaire, STAI, State Trait Anxiety Inventory