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Table 4 Results of the multivariable regression analyses for the WHOQOL-BREF (p < 0.05)

From: The association of depressive symptoms, personality traits, and sociodemographic factors with health-related quality of life and quality of life in patients with advanced-stage lung cancer: an observational multi-center cohort study

Independent variables N B SE β P-value Corrected P-valuea 95% CI for B R2
  General facet
 Age 117 −0.041 0.015 −0.232 0.006 0.024 −0.070, − 0.012 0.402
 CES-D   −0.133 0.021 −0.625 < 0.001 < 0.001 −0.175, − 0.091  
Physical health
 ECOG: 0 to 1 versus 2 or higher 117 −2.747 0.751 −0.262 < 0.001 < 0.001 −4.234, −1.259 0.517
 CES-D   −0.221 0.035 −0.542 < 0.001 < 0.001 −0.291, − 0.151  
 NEO-FFI conscientiousness   0.111 0.045 0.201 0.016 0.043 0.021, 0.200  
  Psychological health
 CES-D 117 −0.163 0.025 −0.534 < 0.001 0.000 −0.213, − 0.113 0.554
  Social relationships
 Gender 119 1.107 0.467 0.222 0.020 0.080 0.181, 2.032 0.204
 Partner status: no partner versus having a partner   1.428 0.588 0.216 0.017 0.080 0.262,
2.594
 
  Environment
 CES-D 116 −0.063 0.028 −0.224 0.026 0.091 −0.118,
− 0.008
0.375
 STAI Trait   −0.163 0.049 −0.392 0.001 0.007 −0.259,
− 0.066
 
  1. aBenjamini-Hochberg method was used to correct P-values
  2. Abbreviations: WHOQOL-BREF World Health Organization Quality of Life-BREF questionnaire, N number of patients, B unstandardized beta, SE standard error, β standardized beta, CI confidence interval, R2 explained varriance, CES-D Center for Epidemiologic Studies Depression Scale, ECOG Eastern Cooperative Oncology Group, NEO-FFI Neuroticism-Extraversion-Openness-Five Factor Inventory questionnaire, STAI, State Trait Anxiety Inventory