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Table 4 Univariate and multivariate analyses for prognostic value of frequent mutations in the subtypes of ICCs

From: Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma

Clinical variablesDFS in large duct typeOS in large duct typeDFS in small duct typeOS in small duct type
Univariate
P-value
Multivariate P-valve/
HR (95% CI)
Univariate
P-value
Multivariate P-valve/
HR (95% CI)
Univariate
P-value
Multivariate P-valve/
HR (95% CI)
Univariate
P-value
Multivariate P-valve/
HR (95% CI)
IDH1/2    0.0090.0220.1260.114
 Mutant vs. wild     3..452 (1.191–10.004) 2.686 (0.789–9.144)
BAP10.0310.0590.0410.0390.952 0.454 
 Loss vs. retained 1.711 (0.979–2.990) 2.985 (1.038–4.186)    
ARID1A0.432 0.580 0.357 0.626 
 Loss vs. retained        
PBRM10.672 0.159 0.284 0.614 
 Loss vs. retained