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Table 4 Univariate and multivariate analyses for prognostic value of frequent mutations in the subtypes of ICCs

From: Distinct clinical and prognostic implication of IDH1/2 mutation and other most frequent mutations in large duct and small duct subtypes of intrahepatic cholangiocarcinoma

Clinical variables

DFS in large duct type

OS in large duct type

DFS in small duct type

OS in small duct type

Univariate

P-value

Multivariate P-valve/

HR (95% CI)

Univariate

P-value

Multivariate P-valve/

HR (95% CI)

Univariate

P-value

Multivariate P-valve/

HR (95% CI)

Univariate

P-value

Multivariate P-valve/

HR (95% CI)

IDH1/2

    

0.009

0.022

0.126

0.114

 Mutant vs. wild

     

3..452 (1.191–10.004)

 

2.686 (0.789–9.144)

BAP1

0.031

0.059

0.041

0.039

0.952

 

0.454

 

 Loss vs. retained

 

1.711 (0.979–2.990)

 

2.985 (1.038–4.186)

    

ARID1A

0.432

 

0.580

 

0.357

 

0.626

 

 Loss vs. retained

        

PBRM1

0.672

 

0.159

 

0.284

 

0.614

 

 Loss vs. retained

        
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BMC Cancer

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