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Table 1 Patient characteristics

From: Retrospective analysis of salvage surgery for local progression of brain metastasis previously treated with stereotactic irradiation: diagnostic contribution, functional outcome, and prognostic factors

 No. (%)
Patients48
Lesions54
Median overall survival from surgery (months)20.2
Median age at surgery (years)63.5
Median time from STI to surgery (months)12
Gender
 Male32 (66.7)
 Female16 (33.3)
Primary cancer
 Lung31 (64.6)
 Breast9 (18.8)
 Others8 (16.6)
Location
 Supratentrial47 (87)
 Infratentrial7 (13)
Neurological deficit
 Yes36 (67)
 No18 (33)
RPA classification at surgery
 Class17 (13)
 Class218 (33)
 Class329 (53)
Radiotherapy before salvage surgery
 STI46 (85)
  SRS24 (44.5)
  SRT17 (31.5)
  Repeated STI5 (9)
 WBRT+STI8 (15)
Surgical method
 Minimum resection26 (48)
  with radiotherapy12 (22)
  without radiotherapy14 (26)
 Resection with free margine28 (52)
Pathological diagnosis
 Tumor recurrence + Necrosis47 (87)
 Radiation necrosis alone7 (13)
Extent of resection
 Gross total removal48 (89)
 Subtotal removal6 (11)
KPS before surgery
 90–10018 (33)
 70–805 (9)
 50–6020 (37)
 30–4011 (20)
 0–200 (0)
KPS after surgery
 90–10024 (44)
 70–8016 (30)
 50–6010 (18.5)
 30–403 (5.5)
 0–201 (2)
Radiotherapy after salvage surgery
 Yes20 (38)
  WBRT10 (18.5)
  STI10 (18.5)
 No34 (62)
Treatment period
 2002–201019 (40)
 2011–201929 (60)