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Table 1 Patient characteristics

From: Retrospective analysis of salvage surgery for local progression of brain metastasis previously treated with stereotactic irradiation: diagnostic contribution, functional outcome, and prognostic factors

 

No. (%)

Patients

48

Lesions

54

Median overall survival from surgery (months)

20.2

Median age at surgery (years)

63.5

Median time from STI to surgery (months)

12

Gender

 Male

32 (66.7)

 Female

16 (33.3)

Primary cancer

 Lung

31 (64.6)

 Breast

9 (18.8)

 Others

8 (16.6)

Location

 Supratentrial

47 (87)

 Infratentrial

7 (13)

Neurological deficit

 Yes

36 (67)

 No

18 (33)

RPA classification at surgery

 Class1

7 (13)

 Class2

18 (33)

 Class3

29 (53)

Radiotherapy before salvage surgery

 STI

46 (85)

  SRS

24 (44.5)

  SRT

17 (31.5)

  Repeated STI

5 (9)

 WBRT+STI

8 (15)

Surgical method

 Minimum resection

26 (48)

  with radiotherapy

12 (22)

  without radiotherapy

14 (26)

 Resection with free margine

28 (52)

Pathological diagnosis

 Tumor recurrence + Necrosis

47 (87)

 Radiation necrosis alone

7 (13)

Extent of resection

 Gross total removal

48 (89)

 Subtotal removal

6 (11)

KPS before surgery

 90–100

18 (33)

 70–80

5 (9)

 50–60

20 (37)

 30–40

11 (20)

 0–20

0 (0)

KPS after surgery

 90–100

24 (44)

 70–80

16 (30)

 50–60

10 (18.5)

 30–40

3 (5.5)

 0–20

1 (2)

Radiotherapy after salvage surgery

 Yes

20 (38)

  WBRT

10 (18.5)

  STI

10 (18.5)

 No

34 (62)

Treatment period

 2002–2010

19 (40)

 2011–2019

29 (60)