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Table 1 Pre-HIIT Outcomes

From: Preoperative exercise to improve fitness in patients undergoing complex surgery for cancer of the lung or oesophagus (PRE-HIIT): protocol for a randomized controlled trial

Outcome

Instrument

Diagnosis

Baseline

Post-intervention

Post-Operatively

Dx

T0

T1

Primary outcome

 Cardiorespiratory fitness

Cardiopulmonary Exercise Test (CPET)

X

X

X

 

Secondary outcomes

Pulmonary and Physical Performance

  Functional performance

Short Physical Performance Battery (SPPB)

X

X

X

 

  Muscle Strength

Leg Press 1-RM

X

X

X

 

  Physical activity

International Physical Activity Questionnaire

X

X

X

 

  Pulmonary Function

CPET

X

X

X

 

  Maximum Inspiratory Pressure

PowerBreathe K-series

X

X

X

 

  Nutritional Status

Dietary interview

X

X

X

 

  Quality of Life

EORTC-QLQ-C30

X

X

X

X

  Cancer specific quality of Life

EORTC-QLQ-OG25 (oesophago-gastric cancer)

X

X

X

X

 

EORTC-QLQ-LC 13 (lung cancer)

X

X

X

X

Qualitative approach

Semi –structured interviews (focus groups or 1:1)

  

X

 

Cost analyses

EQ5D

   

X

 

Service Use Inventory

   

X

Post-operative morbidity

 Post-operative outcomes

Self-reported Functional Recovery

   

X

Post-Operative Morbidity Score

   

X

Clavien Dindo Score

   

X

Comprehensive Complications Index

   

X

Other

 Adherence

Record in case report form/ exercise diary

  

X

 

 Sociodemographic details

Participant self-report

 

X

  

 Body composition

Anthropometry

 

X

X

 

 Cancer/Surgery history

Medical records

 

X

  

 Adverse events

Reports of patients/ research personnel

  

X