Table 5 Univariate and multivariate analysis of lymph node failure in patient with hypopharyngeal carcinoma treated by intensity-modulated radiotherapy (N = 77)
Variable | Ipsilateral nodal failure N = 21 | Contralateral/Bilateral nodal failure N = 3 | Univariate Odds ratio (95% CI) | P value | Multivariate Odds ratio (95% CI) | P value |
|---|---|---|---|---|---|---|
Age (years) | 1.488 (0.555–3.992) | 0.429 | 1.777 (0.545–5.797) | 0.340 | ||
41–58 | 12 | 2 | ||||
58–82 | 9 | 1 | ||||
TNM stage | 1.104 (1.012–1.204) | 0.120 | 0.875 (0.141–5.420) | 0.886 | ||
II | 0 | 0 | ||||
III | 5 | 0 | ||||
IV | 16 | 3 | ||||
Clinical T stage | 1.520 (0.548–4.215) | 0.420 | 1.414 (0.749–2.670) | 0.285 | ||
T1 | 3 | 1 | ||||
T2 | 5 | 0 | ||||
T3 | 8 | 2 | ||||
T4 | 5 | 0 | ||||
Clinical N stage | 0.627 (0.222–1.772) | 0.377 | 0.812 (0.225–2.937) | 0.751 | ||
N0 | 1 | 0 | ||||
N1 | 5 | 0 | ||||
N2 | 13 | 3 | ||||
N3 | 2 | 0 | ||||
rENE | 12.25 (3.353–44.75) | < 0.001 | 11.07 (2.870–42.69) | < 0.001 | ||
Yes | 11 | 1 | ||||
No | 10 | 2 | ||||
Chemotherapy | 0.761 (0.200–2.894) | 0.668 | 0.500 (0.106–2.359) | 0.381 | ||
Yes | 17 | 3 | ||||
No | 4 | 0 |