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Table 1 Correlation between clinicopathological factors and MMR protein expression

From: Characterization of LGR5 expression in poorly differentiated colorectal carcinoma with mismatch repair protein deficiency

 

n

MMR protein

P-value

Proficient

Deficient

Sex

 Male

14

7

7

0.363

 Female

15

10

5

 

Age

  ≥ 71

15

12

3

0.016*

  < 71

14

5

9

 

Tumor site

 Proximal

17

7

10

0.023*

 Distal

12

10

2

 

Lymphovascular invasion

 Absent

0

0

0

NA

 Present

29

17

12

 

Lymph node metastasis

 Absent

9

0

9

< 0.001*

 Present

20

17

3

 

Pathological stage

  ≤ pT2

7

0

7

< 0.001*

  > pT3

22

17

5

 

CD8+ TILs

  ≤ 155.7

15

15

0

< 0.001*

  > 155.7

14

2

10

 
  1. TIL tumor-infiltrating lymphocytes
  2. * P < 0.05