Table 5 Clinicopathologic characteristics
Characteristic | Without postoperative chemotherapy (n = 112) | With postoperative chemotherapy (n = 15) | P |
|---|---|---|---|
Age (years) | 56.19 ± 9.79 | 55.13 ± 7.94 | 0.690 |
Male | 59 (52.7) | 10 (66.7) | 0.307 |
Location | 0.203 | ||
Hilar | 18 (16.1) | 5 (33.3) | |
Peripheral | 94 (83.9) | 10 (66.7) | |
HBsAg | 0.494 | ||
Negative | 81 (72.3) | 9 (60.0) | |
Positive | 31 (27.7) | 6 (40.0) | |
Tumor size (cm) | 0.110 | ||
≤ 5 | 43 (38.4) | 9 (60.0) | |
> 5 | 69 (61.6) | 6 (40.0) | |
Multiple tumor | 0.315 | ||
No | 79 (70.5) | 13 (86.7) | |
Yes | 33 (29.5) | 2 (13.3) | |
Vascular invasion | 0.538 | ||
No | 69 (61.6) | 8 (53.3) | |
Yes | 43 (38.4) | 7 (46.7) | |
Capsular invasion | 0.371 | ||
No | 61 (54.5) | 10 (66.7) | |
Yes | 51 (45.5) | 5 (33.3) | |
Visceral invasion | 0.127 | ||
No | 90 (80.4) | 15 (100.0) | |
Yes | 22 (19.6) | 0 (0.0) | |
AJCC T stage | 0.250 | ||
1 and 2 | 57 (50.9) | 10 (66.7) | |
3 and 4 | 55 (49.1) | 5 (33.3) | |
AJCC N stage | 0.967 | ||
0 | 74 (66.1) | 10 (66.7) | |
1 | 25 (22.3) | 3 (20.0) | |
x | 13 (11.6) | 2 (13.3) | |
AJCC tumor stage | 0.364 | ||
I | 28 (25.0) | 6 (40.0) | |
II | 18 (16.1) | 1 (6.7) | |
III | 66 (58.9) | 8 (53.3) | |
Tumor differentiation | 0.643 | ||
Well to moderate | 38 (33.9) | 6 (40.0) | |
Poor to undifferentiated | 74 (66.1) | 9 (60.0) | |
Liver cirrhosis | 0.450 | ||
No | 71 (63.4) | 11 (73.3) | |
Yes | 41 (36.6) | 4 (26.7) | |
ALT (U/L) | 0.163 | ||
≤ 40 | 73 (65.2) | 7 (46.7) | |
> 40 | 39 (34.8) | 8 (53.3) | |
AST (U/L) | 0.297 | ||
≤ 40 | 75 (67.0) | 8 (53.3) | |
> 40 | 37 (33.0) | 7 (46.7) | |
PLT (×10^9/L) | 232.32 ± 94.43 | 208.60 ± 87.96 | 0.359 |
CEA (ng/ml) | 0.859 | ||
≤ 5 | 83 (74.1) | 12 (80.0) | |
> 5 | 29 (25.9) | 3 (20.0) | |
CA19–9 (U/ml) | 0.482 | ||
≤ 200 | 64 (57.1) | 10 (66.7) | |
> 200 | 48 (42.9) | 5 (33.3) | |
CA242 (U/ml) | 0.910 | ||
≤ 20 | 58 (51.8) | 8 (53.3) | |
> 20 | 54 (48.2) | 7 (46.7) | |
Child-Pugh score | 0.228 | ||
A | 99 (88.4) | 11 (73.3) | |
B | 13 (11.6) | 4 (26.7) | |
Perineural invasion | 0.482 | ||
No | 64 (57.1) | 10 (66.7) | |
Yes | 48 (42.9) | 5 (33.3) | |
Post-recurrence anti-tumor therapy | 0.489 | ||
Yes | 72 (64.3) | 11 (73.3) | |
No | 40 (35.7) | 4 (26.7) |