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Table 4 The association of RIPK1 gene polymorphisms with cervical cancer susceptibility in Uygur population

From: RIPK1 polymorphisms alter the susceptibility to cervical Cancer among the Uyghur population in China

SNPModelAllele/GenotypeFrequency (Control/Case)OR (95%CI)P ValueFDR-p Value
rs6907943AlleleC15.59%/15.69%1.01 (0.77–1.32)0.9580.958
 A84.41%/84.31%1.00  
CodominantCC2.62%/4.40%1.65 (0.77–3.52)0.1990.597
 CA25.96%/22.58%0.85 (0.61–1.18)0.3330.666
 AA71.42%/73.02%1.00  
DominantCC-CA28.58%/26.98%0.92 (0.68–1.26)0.6160.924
 AA71.42%/73.02%1.00  
RecessiveCC2.62%/4.40%1.72 (0.81–3.65)0.1620.597
 CA-AA97.38%/95.60%1.00  
Log-additive  1.01 (0.78–1.31)0.9560.958
rs2077681AlleleC15.96%/18.62%1.21 (0.93–1.56)0.1550.245
 T84.04%/81.38%1.00  
CodominantCC1.82%/5.57%3.14 (1.40–7.07)0.0060.018
 CT28.28%/26.10%0.94 (0.69–1.29)0.7110.711
 TT69.90%/68.33%1.00  
DominantCC-CT30.10%/31.67%1.08 (0.80–1.45)0.6340.711
 TT69.90%/68.33%1.00  
RecessiveCC1.82%/5.57%3.20 (1.43–7.16)0.0050.018
 CT-TT98.18%/94.43%1.00  
Log-additive  1.20 (0.93–1.54)0.1630.245
rs9503400AlleleA4.92%/6.58%1.36 (0.90–2.07)0.1460.271
 G95.08%/93.42%1.00  
CodominantAA0.20%/0.88%4.46 (0.46–43.25)0.1970.271
 GA9.44%/11.40%1.25 (0.79–1.95)0.3390.339
 GG90.36%/87.72%1.00  
DominantAA-GA9.64%/12.28%1.31 (0.85–2.04)0.2260.271
 GG90.36%/87.72%1.00  
RecessiveAA0.20%/0.88%4.36 (0.45–42.26)0.2030.271
 GA-GG99.8%/99.12%1.00  
Log-additive  1.35 (0.89–2.03)0.1550.271
rs17548629AlleleT14.06%/13.45%0.95 (0.72–1.26)0.7240.724
 C85.94%/86.55%1.00  
CodominantTT1.81%/2.92%1.57 (0.63–3.92)0.3340.663
 TC24.50%/21.05%0.83 (0.60–1.16)0.2770.663
 CC73.69%/76.03%1.00  
DominantTT-TC26.31%/23.97%0.88 (0.64–1.21)0.4420.663
 CC73.69%/76.03%1.00  
RecessiveTT1.81%/2.92%1.64 (0.66–4.07)0.2890.663
 TC-CC98.19%/97.08%1.00  
Log-additive  0.95 (0.72–1.26)0.7240.724
  1. SNP Sing nucleotide polymorphism, OR Odds ratios, CI Confidence intervals, FDR False discovery ratel
  2. Bold italics indicates the SNP with statistical significance (p < 0.05)