Fig. 3

SLC6A1 overexpression promotes the tumor growth in vivo. a and b Comparison of tumor volumes obtained from different groups. Representative photographs of tumors in mouse models established using PC3 cells transfected with SLC6A1 expression vector or the specific shRNA. c Representative photographs of immunohistochemistry analysis on the expression levels of PCNA andMMP-9 proteins in tumor tissues obtained from mouse models established using PC3 cells transfected with SLC6A1 expression vector or the specific shRNA. Magnification of the left panel is × 100; the right panel is × 400. d The immunoreactivity score of the expression levels of PCNA andMMP-9 proteins in tumor tissues