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Table 2 Common altered transportome genes in HS versus ML in both nCounter and cell microarray

From: The A818–6 system as an in-vitro model for studying the role of the transportome in pancreatic cancer

Gene SymbolDescriptionFC nCounterCell microarray
mean of 2 exp.FCadj. p-value
KCNF1potasium voltage-gated channel, subfamily F, member 167.465475.040.03
SCNN1Bsodium channel, no volateg-gated 1, beta29.38547.450.034
KCNQ1potasium voltage-gated channel, KQT-like subfamily, member 19.878.590.012
SLC7A2solute carrier family 7 (cationic amino acid transporter, y + system)6.6810.830.028
CACNA1Dcalcium channel, voltage-dependant, L-type, alpha 1D subunit5.945.050,008
TRPV6transient receptor potential cation channel, subfamily V, member 63.5355.370.035
SLC4A4solute carrier family 4, sodium bicarbonate cotransporter, member 43.03534.410.017
SLC26A11solute carrier family 26, member 112.7452.480.003
SLC1A4solute carrier family 1 (glutmate/neutral amino acid transporter, member 42.534.160.026
SLC41A1solute carrier family 41, member
HCN3hyperpolarization activated cyclic nucleotide-gated potassium channel 31.6552.090.005
ABCG1ATP binding cassette, subfamily G (WHITE), member 1−1.85− 5.510.008
SLC1A1solute carrier family 1 (neuronal/epithelial high affinity glutmate transporter, system Xag), member 1−2.025−2.510.027
SLC38A6solute carrier family 38, member 6 (SLC38A6), transript variant 2−2.19−3.50.018
GJC1gap junction protein, gamma 1, 45 kDa−2.255−2.830.007
GJB2gap junction protein, beta 2, 26 kDa−2.63−2.340.006
SLC16A7solute carrier family 16, member 7 (monocarboxylic acid transporter 2; MCT2)−2.7−4.160.0034
SLC20A1solute carrier family 20, (phosphate transporter), member 1−2.93−2.030.045
LDHBlactate dehydrogenase B−3.12−2.590.008
LDHAlactate dehydrogenase A, (LDHA), transcript 1−4.095−3.830.005
GJB5gap junction protein, beta 5, 31.1 kDa−5.07−5.20.008
SLC29A1solute carrier family 29 (nucleoside tranaporter), member 1, mitochondrial protein−5.135− 5.460.008
GJB4gap junction protein, beta 4, 30.3 kDa−5.605−3.780.012
GJB3gap junction protein, beta 3, 31 kDa−5.9−5.30.015
SLC16A1solute carrier family 16, member 1 (monocarboxylic acid transporter 1; MCT1)−20.05−52.80.021
GJA5gap junction protein, alpha 5, 40 kDa−20.69−16.260.008