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Table 2 Common altered transportome genes in HS versus ML in both nCounter and cell microarray

From: The A818–6 system as an in-vitro model for studying the role of the transportome in pancreatic cancer

Gene Symbol Description FC nCounter Cell microarray
mean of 2 exp. FC adj. p-value
KCNF1 potasium voltage-gated channel, subfamily F, member 1 67.465 475.04 0.03
SCNN1B sodium channel, no volateg-gated 1, beta 29.385 47.45 0.034
KCNQ1 potasium voltage-gated channel, KQT-like subfamily, member 1 9.87 8.59 0.012
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y + system) 6.68 10.83 0.028
CACNA1D calcium channel, voltage-dependant, L-type, alpha 1D subunit 5.94 5.05 0,008
TRPV6 transient receptor potential cation channel, subfamily V, member 6 3.535 5.37 0.035
SLC4A4 solute carrier family 4, sodium bicarbonate cotransporter, member 4 3.035 34.41 0.017
SLC26A11 solute carrier family 26, member 11 2.745 2.48 0.003
SLC1A4 solute carrier family 1 (glutmate/neutral amino acid transporter, member 4 2.53 4.16 0.026
SLC41A1 solute carrier family 41, member 1 2.03 2.24 0.008
HCN3 hyperpolarization activated cyclic nucleotide-gated potassium channel 3 1.655 2.09 0.005
ABCG1 ATP binding cassette, subfamily G (WHITE), member 1 −1.85 − 5.51 0.008
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutmate transporter, system Xag), member 1 −2.025 −2.51 0.027
SLC38A6 solute carrier family 38, member 6 (SLC38A6), transript variant 2 −2.19 −3.5 0.018
GJC1 gap junction protein, gamma 1, 45 kDa −2.255 −2.83 0.007
GJB2 gap junction protein, beta 2, 26 kDa −2.63 −2.34 0.006
SLC16A7 solute carrier family 16, member 7 (monocarboxylic acid transporter 2; MCT2) −2.7 −4.16 0.0034
SLC20A1 solute carrier family 20, (phosphate transporter), member 1 −2.93 −2.03 0.045
LDHB lactate dehydrogenase B −3.12 −2.59 0.008
LDHA lactate dehydrogenase A, (LDHA), transcript 1 −4.095 −3.83 0.005
GJB5 gap junction protein, beta 5, 31.1 kDa −5.07 −5.2 0.008
SLC29A1 solute carrier family 29 (nucleoside tranaporter), member 1, mitochondrial protein −5.135 − 5.46 0.008
GJB4 gap junction protein, beta 4, 30.3 kDa −5.605 −3.78 0.012
GJB3 gap junction protein, beta 3, 31 kDa −5.9 −5.3 0.015
SLC16A1 solute carrier family 16, member 1 (monocarboxylic acid transporter 1; MCT1) −20.05 −52.8 0.021
GJA5 gap junction protein, alpha 5, 40 kDa −20.69 −16.26 0.008