Table 2 Common altered transportome genes in HS versus ML in both nCounter and cell microarray
Gene Symbol | Description | FC nCounter | Cell microarray | |
|---|---|---|---|---|
mean of 2 exp. | FC | adj. p-value | ||
KCNF1 | potasium voltage-gated channel, subfamily F, member 1 | 67.465 | 475.04 | 0.03 |
SCNN1B | sodium channel, no volateg-gated 1, beta | 29.385 | 47.45 | 0.034 |
KCNQ1 | potasium voltage-gated channel, KQT-like subfamily, member 1 | 9.87 | 8.59 | 0.012 |
SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y + system) | 6.68 | 10.83 | 0.028 |
CACNA1D | calcium channel, voltage-dependant, L-type, alpha 1D subunit | 5.94 | 5.05 | 0,008 |
TRPV6 | transient receptor potential cation channel, subfamily V, member 6 | 3.535 | 5.37 | 0.035 |
SLC4A4 | solute carrier family 4, sodium bicarbonate cotransporter, member 4 | 3.035 | 34.41 | 0.017 |
SLC26A11 | solute carrier family 26, member 11 | 2.745 | 2.48 | 0.003 |
SLC1A4 | solute carrier family 1 (glutmate/neutral amino acid transporter, member 4 | 2.53 | 4.16 | 0.026 |
SLC41A1 | solute carrier family 41, member 1 | 2.03 | 2.24 | 0.008 |
HCN3 | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 1.655 | 2.09 | 0.005 |
ABCG1 | ATP binding cassette, subfamily G (WHITE), member 1 | −1.85 | − 5.51 | 0.008 |
SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutmate transporter, system Xag), member 1 | −2.025 | −2.51 | 0.027 |
SLC38A6 | solute carrier family 38, member 6 (SLC38A6), transript variant 2 | −2.19 | −3.5 | 0.018 |
GJC1 | gap junction protein, gamma 1, 45 kDa | −2.255 | −2.83 | 0.007 |
GJB2 | gap junction protein, beta 2, 26 kDa | −2.63 | −2.34 | 0.006 |
SLC16A7 | solute carrier family 16, member 7 (monocarboxylic acid transporter 2; MCT2) | −2.7 | −4.16 | 0.0034 |
SLC20A1 | solute carrier family 20, (phosphate transporter), member 1 | −2.93 | −2.03 | 0.045 |
LDHB | lactate dehydrogenase B | −3.12 | −2.59 | 0.008 |
LDHA | lactate dehydrogenase A, (LDHA), transcript 1 | −4.095 | −3.83 | 0.005 |
GJB5 | gap junction protein, beta 5, 31.1 kDa | −5.07 | −5.2 | 0.008 |
SLC29A1 | solute carrier family 29 (nucleoside tranaporter), member 1, mitochondrial protein | −5.135 | − 5.46 | 0.008 |
GJB4 | gap junction protein, beta 4, 30.3 kDa | −5.605 | −3.78 | 0.012 |
GJB3 | gap junction protein, beta 3, 31 kDa | −5.9 | −5.3 | 0.015 |
SLC16A1 | solute carrier family 16, member 1 (monocarboxylic acid transporter 1; MCT1) | −20.05 | −52.8 | 0.021 |
GJA5 | gap junction protein, alpha 5, 40 kDa | −20.69 | −16.26 | 0.008 |