Dietary factors and risk of mortality among patients with esophageal cancer: a systematic review

BMC Cancer

Table 2 Hazard ratios (HRs) with 95% confidence intervals (CIs) for alcohol consumption and mortality of esophageal cancer by histological type

Study ID ^a	Crude HR (95% CI) ^b	Adjusted HR (95% CI) ^b	Heterogeneity for pooled crude HR		Heterogeneity for pooled adjusted HR
Study ID ^a	Crude HR (95% CI) ^b	Adjusted HR (95% CI) ^b	I² (%)	P	I² (%)	P
EC			/	/	4.2	0.352
Huang et al. [27]		1.46 (1.19,1.79)
Samadi et al. [33]		7.51 (0.82, 69.10)
Park et al. [28]		1.44 (0.81, 2.55)
pooled estimates		1.48 (1.19, 1.84)
ESCC			77.8	0.001	66.9	0.010
Huang et al. [27]		1.37 (1.11, 1.70)
Ma et al. [15]		1.58 (1.21, 2.07)
Shitara et al. [26]	0.87 (0.65, 1.17)	0.85 (0.61, 1.18)
Sundelof et al. [14]		0.60 (0.30, 1.40)
Thrift et al. [29]	2.51 (1.63, 3.85)	2.08 (1.18, 3.69)
Trivers et al. [23]	1.77 (0.93, 3.35)
Wu et al. [32]		1.30 (1.01, 1.67)
Jing et al. [25]	1.42 (0.83, 1.84)
Lu et al. [24]	1.02 (0.61, 1.72)
pooled estimates	1.27 (1.06, 1.53)	1.26(1.01, 1.60)
EAC			/	/	0.0	0.960
Sundelof et al. [14]		1.00 (0.50, 1.70)
Thrift et al. [31]		1.02 (0.64, 1.64)
Trivers et al. [23]	1.08 (0.81, 1.44)
pooled estimates		1.01 (0.70, 1.47)

^aEC esophageal cancer, ESCC esophageal squamous cell carcinoma, EAC esophageal adenocarcinoma, HR hazard ratio, CI confidence interval
^b The effect was estimated by comparing the highest with the lowest consumption of alcohol

ISSN: 1471-2407