Table 2 Characteristics of patients in subgroups of accurate-N-staging, over-N-staging and under-N-staging
From: Risk factor analysis for inaccurate pre-operative MRI staging in rectal cancer
Characteristics | Accurate-N-staging | Over-N-staging | Under-N-staging | P Value |
|---|---|---|---|---|
Cases | 398 (70.7%) | 78 (13.9%) | 75 (13.3%) | |
Gender | ||||
Female | 171 (43%) | 31 (39.7%) | 31 (41.3%) | 0.853 |
Male | 227 (57%) | 47 (60.3%) | 44 (58.7%) | |
Age | 60.0 ± 13.2 | 58.2 ± 14.3 | 58.7 ± 14.4 | 0.514 |
BMI | 22.5 ± 3.52 | 21.8 ± 4.31 | 23.3 ± 6.44 | 0.048 |
DM | 0.709 | |||
No | 366 (93.6%) | 73 (96.1%) | 68 (93.2%) | |
Yes | 25 (6.4%) | 3 (3.9%) | 5 (6.8%) | |
CEA | 2.69 (0–117) | 3.08 (1–255) | 2.94 (0–81) | 0.152 |
CA199 | 10.27 (0–2188) | 9.57 (0–322) | 10.59 (0–723) | 0.491 |
Bowel Obstruction | < 0.001 | |||
No | 354 (91.5%) | 53 (68.8%) | 64 (86.5%) | |
Yes | 33 (8.5%) | 24 (31.2%) | 10 (13.5%) | |
WBC | 6.37 ± 1.82 | 7.31 ± 2.44 | 6.56 ± 1.71 | 0.924 |
HB | 125.8 ± 20.3 | 119.5 ± 21.7 | 121.3 ± 26.3 | 0.053 |
PLT | 226.9 ± 75.3 | 257.1 ± 91.7 | 253.5 ± 72.8 | 0.001* |
ALB | 41.6 ± 6.74 | 40.5 ± 5.12 | 42.2 ± 4.58 | 0.216 |
Tumor Location | 0.6 | |||
Upper | 152 (38.2%) | 35 (44.9%) | 30 (40%) | |
Middle | 100 (25.1%) | 22 (28.2%) | 19 (25.3%) | |
Low | 146 (36.7%) | 21 (26.9%) | 26 (34.7%) | |
Tumor Size (cm) | 4.11 ± 3.48 | 5.59 ± 3.11 | 4.11 ± 1.71 | < 0.001** |
Histological Subtype | < 0.001 | |||
Classic adenocarcinoma | 374 (94.2%) | 72 (92.3%) | 59 (79.7%) | |
Mucinous adenocarcinoma | 23 (5.8%) | 6 (7.7%) | 15 (20.3%) | |
Differentiation | 0.298 | |||
Well/Moderate | 349 (93.3%) | 68 (90.7%) | 54 (88.5%) | |
Poor | 25 (6.7%) | 7 (9.3%) | 7 (11.5%) | |
MMR Status | 0.3 | |||
pMMR | 251 (94.7%) | 52 (89.7%) | 47 (95.9%) | |
dMMR | 14 (5.3%) | 6 (10.3%) | 2 (4.1%) | |
Ras Mutation | 0.483 | |||
No | 355 (89.2%) | 73 (93.6%) | 68 (90.7%) | |
Yes | 43 (10.8%) | 5 (6.4%) | 7 (9.3%) | |