Skip to main content

Table 2 Characteristics of patients in subgroups of accurate-N-staging, over-N-staging and under-N-staging

From: Risk factor analysis for inaccurate pre-operative MRI staging in rectal cancer

CharacteristicsAccurate-N-stagingOver-N-stagingUnder-N-stagingP Value
Cases398 (70.7%)78 (13.9%)75 (13.3%) 
Gender
 Female171 (43%)31 (39.7%)31 (41.3%)0.853
 Male227 (57%)47 (60.3%)44 (58.7%) 
Age60.0 ± 13.258.2 ± 14.358.7 ± 14.40.514
BMI22.5 ± 3.5221.8 ± 4.3123.3 ± 6.440.048
DM   0.709
 No366 (93.6%)73 (96.1%)68 (93.2%) 
 Yes25 (6.4%)3 (3.9%)5 (6.8%) 
CEA2.69 (0–117)3.08 (1–255)2.94 (0–81)0.152
CA19910.27 (0–2188)9.57 (0–322)10.59 (0–723)0.491
Bowel Obstruction   < 0.001
 No354 (91.5%)53 (68.8%)64 (86.5%) 
 Yes33 (8.5%)24 (31.2%)10 (13.5%) 
WBC6.37 ± 1.827.31 ± 2.446.56 ± 1.710.924
HB125.8 ± 20.3119.5 ± 21.7121.3 ± 26.30.053
PLT226.9 ± 75.3257.1 ± 91.7253.5 ± 72.80.001*
ALB41.6 ± 6.7440.5 ± 5.1242.2 ± 4.580.216
Tumor Location   0.6
 Upper152 (38.2%)35 (44.9%)30 (40%) 
 Middle100 (25.1%)22 (28.2%)19 (25.3%) 
 Low146 (36.7%)21 (26.9%)26 (34.7%) 
Tumor Size (cm)4.11 ± 3.485.59 ± 3.114.11 ± 1.71< 0.001**
Histological Subtype   < 0.001
 Classic adenocarcinoma374 (94.2%)72 (92.3%)59 (79.7%) 
 Mucinous adenocarcinoma23 (5.8%)6 (7.7%)15 (20.3%) 
Differentiation   0.298
 Well/Moderate349 (93.3%)68 (90.7%)54 (88.5%) 
 Poor25 (6.7%)7 (9.3%)7 (11.5%) 
MMR Status   0.3
 pMMR251 (94.7%)52 (89.7%)47 (95.9%) 
 dMMR14 (5.3%)6 (10.3%)2 (4.1%) 
Ras Mutation   0.483
 No355 (89.2%)73 (93.6%)68 (90.7%) 
 Yes43 (10.8%)5 (6.4%)7 (9.3%) 
  1. Abbreviations: BMI body mass index, CEA carcinoembryonic antigen, WBC white blood cell, HB hemoglobin, PLT plate, ALB albumin, pMMR mismatch repair-proficient, dMMR mismatch repair-deficient
  2. *Post Hoc Test: Accurate-N-staging vs over-N-staging, P = 0.002; Accurate-N-staging vs under-N-staging, P = 0.011
  3. **Post Hoc Test: Accurate-N-staging vs over-N-staging, P < 0.001