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Table 1 Characteristics of patients in subgroups of accurate-T-staging, over-T-staging and under-T-staging

From: Risk factor analysis for inaccurate pre-operative MRI staging in rectal cancer

CharacteristicsTotalAccurate-T-stagingOver-T-stagingUnder-T-stagingP Value
Cases551392 (69.6%)109 (19.4%)50 (8.9%) 
Gender    0.633
 Female233 (42.3%)169 (43.1%)46 (42.2%)18 (36%) 
 Male318 (57.7%)223 (56.9%)63 (57.8%)32 (64%) 
Age59.7 ± 13.460.2 ± 12.957.3 ± 14.461.3 ± 14.40.102
BMI22.5 ± 4.1922.5 ± 4.422.5 ± 3.822.5 ± 3.40.998
Diabetes Mellitus    0.157
 No507 (93.9%)360 (93%)99 (94.3%)48 (100%) 
 Yes33 (6.1%)27 (7%)6 (5.7%)0 (0%) 
CEA2.73 (0–255)2.7 (0–255)2.7 (0–197)4.5 (1–81)0.62
CA19910.2 (0–2188)10.64 (0–2188)7.59 (0–1156)10.35 (0–117)0.001
Bowel Obstruction    0.008
 No471 (87.5%)350 (89.7%)88 (79.3%)44 (89.8%) 
 Yes67 (12.5%)40 (10.3%)23 (20.7%)5 (10.2%) 
WBC6.53 ± 1.936.54 ± 1.916.53 ± 2.116.48 ± 1.710.984
HB124.3 ± 21.5125.0 ± 19.5123.4 ± 24.4121.1 ± 28.70.433
PLT234.5 ± 78.4237.6 ± 80.1227.2 ± 74.5226.4 ± 72.70.355
ALB41.5 ± 6.3041.6 ± 6.1040.8 ± 6.9642.2 ± 6.370.381
Tumor Location    0.186
 Upper217 (39.4%)163 (41.6%)37 (33.9%)17 (34%) 
 Middle141 (25.6%)101 (25.8%)24 (22%)16 (32%) 
 Low193 (35%)128 (32.7%)48 (44%)17 (34%) 
Tumor Size (cm)4.07 ± 1.694.22 ± 1.703.76 ± 1.703.60 ± 1.370.005*
Histological Subtype    1
 Classic Adenocarcinoma505 (92%)359 (92.1%)100 (91.7%)46 (92%) 
 Mucinous Adenocarcinoma44 (8%)31 (7.9%)9 (8.3%)4 (8%) 
Differentiation    0.824
 Grade 1/2471 (92.4%)337 (92.1%)91 (94.8%)43 (89.6%) 
 Grade 3/439 (7.6%)29 (7.9%)5 (5.2%)5 (10.4%) 
MMR Status    0.823
 pMMR350 (94.1%)17 (6.6%)4 (4.8%)1 (3.1%) 
 dMMR22 (5.9%)239 (93.4%)80 (95.2%)31 (96.9%) 
Ras Mutation    0.322
 No496 (90%)355 (90.6%)99 (90.8%)42 (84%) 
 Yes55 (10%)37 (9.4%)10 (9.2%)8 (16%) 
  1. Abbreviations: BMI body mass index, CEA carcinoembryonic antigen, WBC white blood cell, HB hemoglobin, PLT plate, ALB albumin, pMMR mismatch repair-proficient, dMMR mismatch repair-deficient
  2. *Post Hoc Test: Accurate-T-staging vs over-T-staging, P = 0.012; Accurate-T-staging vs under-T-staging, P = 0.015