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Table 3 Cox proportional hazard model for risk of death

From: PD-L1 and PD-L2 expression in the tumor microenvironment including peritumoral tissue in primary central nervous system lymphoma

 

Hazard Ratio (95% CI)

p value

Age > 60 years

3.61 (1.40–12.31)

0.0056

KPS > 50

0.63 (0.31–1.35)

0.2221

Elevated LDH

2.39 (1.11–4.89)

0.0265

Existence of deep-seated lesion

1.04 (0.48–2.12)

0.9076

Existence of multiple lesions

1.05 (0.53–2.04)

0.8976

EB virus-positive

0.95 (0.33–2.24)

0.9199

PD-L1 positive on tumor cells

1.15 (0.55–2.72)

0.7209

PD-L1 positive on intratumoral macrophage

0.50 (0.25–0.96)

0.0379

PD-L1 positive on peritumoral macrophage

0.30 (0.12–0.77)

0.0129

PD-L2 positive on intratumoral macrophage

0.72 (0.37–1.38)

0.3193

PD-L2 positive on peritumoral macrophage

1.01 (0.39–3.14)

0.9814

Gross total removal (v.s. biopsy)

1.98 (0.76–4.61)

0.1518

Chemotherapy

0.28 (0.12–0.76)

0.0150

Radiation therapy

1.73 (0.81–4.12)

0.1593

  1. KPS Karnofsky performance status