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Table 4 Comparison of clinicopathological characteristics of 255 HER2-positive patients without trastuzumab

From: Roles of neutrophil/lymphocyte ratio in prognosis and in differentiation of potential beneficiaries in HER2-positive breast cancer with trastuzumab therapy

Factors

Group 1

p-value

 

Low pre-NLR

High pre-NLR

Age (year)

  ≤ 40

14 (11.0)

17 (13.3)

0.581

  > 40

113 (89.0)

111 (86.7)

 

T stage

 T1

29 (22.8)

22 (17.2)

 

 T2

82 (64.6)

90 (70.3)

0.515

 T3–4

16 (12.6)

16 (12.5)

 

N stage

 pN0

68 (53.5)

76 (59.4)

 

 pN1

41 (32.3)

35 (27.3)

0.624

 pN2–3

18 (14.2)

17 (13.3)

 

Histological grade

 1~2

98 (77.2)

100 (78.1)

0.854

 3

29 (22.8)

28 (21.9)

 

HR

 Negative

72 (56.7)

73 (57.0)

0.957

 Positive

55 (43.3)

130 (43.0)

 

Ki67 (%)

  < 30

67 (52.8)

57 (44.5)

0.189

  ≥ 30

60 (47.2)

71 (55.5)

 

NC

 No

59 (46.5)

58 (45.3)

0.855

 Yes

68 (53.5)

70 (54.7)

 

Total

127 (100.0)

128 (100.0)

 
  1. NLR neutrophil/lymphocyte ratio, HR hormone receptor, NC neoadjuvant chemotherapy