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Table 1 Descriptive questionnaire data of cases and controls

From: MTHFR, XRCC1 and OGG1 genetic polymorphisms in breast cancer: a case-control study in a population from North Sardinia

Variables

Cases X

Cases n.

Cases %

Contr. X

Contr. n.

Contr. %

P value

Age

57.00

  

50.03

  

9.0E-07a

Height

159.24

  

160.50

  

0.1

Weight

64.50

  

60.20

  

0.002a

BMI

25.40

  

23.40

   

  < 25

 

72

53.33

 

80

71.43

0.004

 25–30

 

38

28.15

 

25

22.32

 

  ≥ 30

 

25

18.52

 

7

6.25

 

Age at menarche

12.44

  

12.72

  

0.1

 7–10

 

12

8.89

 

8

7.14

0.7

 11–13

 

90

66.67

 

72

64.28

 

 14–17

 

33

24.44

 

32

28.58

 

Menopause

 natural menopause

 

62

45.93

 

55

49.11

0.6

 age

49.90

  

48.60

  

0.1

 HRT regimen

 

11

17.74

 

8

14.54

0.6

Parity

 

97

71.85

 

71

63.39

0.2

 first full-term pregnancy

27.59

  

29.56

  

0.1

 number of live birth

2.05

  

1.82

  

0.1

Breastfed

 

78

80.41

 

63

88.73

0.2

 months of breastfeeding

11.83

  

12.72

  

0.9

Oral contraceptive use

 

78

57.77

 

87

77.67

0.001a

 duration of employment:

   ≤ 5 y

 

20

25.64

 

33

37.93

0.2

  6–14 y

 

35

44.87

 

33

37.93

 

   ≥ 15 y

 

23

29.49

 

21

24.14

 

Benign breast lesions

 

29

21.48

 

12

10.71

0.03

BC family

 in first degree relatives

1.34

  

0.74

  

8.8E-05a

  0 cases

 

47

34.81

 

62

55.36

4.0E-04a

  1–2 cases

 

58

42.96

 

42

37.50

 

   ≥ 3

 

30

22.22

 

8

7.14

 

Tumor family

 in first degree relatives:

3.42

  

2.81

  

0.03

  0–2 cases

 

51

37.78

 

57

50.90

0.05

  3–5

 

57

42.22

 

43

38.39

 

   ≥ 6

 

27

20.00

 

12

10.71

 

Alcohol intake

 daily-often

 

31

22.96

 

13

11.61

0.03

 occasionally- nondrinkers

 

104

77.04

 

99

88.39

 

Smoking status (smokers at recruitment)

 

19

14.07

 

18

16.07

0.7

Smokers (at recruitment+ex smokers)

 

68

50.37

 

56

50.00

0.2

 cigarette packs/year:

       

   < 10

 

30

44.12

 

25

44.64

0.3

  10–19

 

16

23.53

 

19

33.93

 

   ≥ 20

 

22

32.35

 

12

21.43

 

 passive smoke:

 

100

74.07

 

87

77.68

5.0E-04a

  little

 

22

22.00

 

41

47.13

 

  moderately

 

46

46.00

 

27

31.03

 

  strong

 

32

32.00

 

19

21.84

 

Osteoporosis

 

41

30.37

 

22

19.64

0.06

Chemical exposure

 

43

31.85

 

18

16.07

0.04

Sport activity (2–3 times a week)

 

45

33.33

 

43

38.39

0.4

Adolescence sport activity

 

36

26.66

 

56

50.00

2.0E-04a

  1. aSignificant after Bonferroni correction
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