Table 2 Meta-analysis of baseline BSI, ΔBSI and subgroup for OS
Stratified analysis | Subgroup | No. of studies | P (heterogeneity) | I2 (%) | Effect model | HR | (95% CI) | P-value | Begg’s test |
|---|---|---|---|---|---|---|---|---|---|
Baseline BSI | Overall | 7 | 0.001 | 72.4 | Random | 1.331 | 1.081–1.640 | 0.007 | 0.764 |
Ethnicity | Caucasian | 2 | 0.009 | 85.3 | Random | 1.102 | 0.906–1.339 | 0.331 | |
Asian | 7 | 0.485 | 0 | Random | 1.688 | 1.297–2.197 | < 0.001 | ||
Cut-off | ≤ 1 | 6 | 0.274 | 22.8 | Random | 1.33 | 1.072–1.650 | 0.009 | |
> 1 | 3 | 0.009 | 78.9 | Random | 1.489 | 0.852–2.604 | 0.162 | ||
ΔBSI | Overall | 5 | 0.027 | 63.4 | Random | 1.22 | 1.015–1.467 | 0.034 | 0.462 |
Ethnicity | Caucasian | 2 | 0.097 | 63.7 | Random | 1.099 | 0.950–1.272 | 0.204 | |
Asian | 3 | 0.377 | 0 | Random | 1.49 | 1.137–1.954 | 0.004 |