Table 2 Correlation of Ki-67 with clinicopathological parameters in gliomas
Clinicopathological parameters | Ki-67 level | P value | ||
|---|---|---|---|---|
Low (< 20) | High (≥ 20) | |||
Age | < 45 | 77 | 35 | < 0.001 |
≥ 45 | 39 | 81 | ||
Epilepsy | No | 70 | 89 | 0.007 |
Yes | 46 | 27 | ||
Pathological type | Malignant astrocytoma | 9 | 4 | < 0.001 |
Malignant oligodendroglioma | 2 | 11 | ||
Glioblastoma | 16 | 82 | ||
Diffuse glioma | 30 | 6 | ||
Oligodendroglioma | 25 | 0 | ||
Astrocytoma | 16 | 1 | ||
Other | 18 | 12 | ||
Tumor grade | 1–2 | 71 | 1 | < 0.001 |
3–4 | 42 | 113 | ||
Lesion number | Single | 112 | 103 | 0.023 |
Multiple | 4 | 13 | ||
KPS | < 85 | 58 | 76 | 0.017 |
≥ 85 | 58 | 40 | ||
NeuN | Positive | 21 | 7 | 0.003 |
Negative | 86 | 106 | ||
EMA | Positive | 7 | 32 | < 0.001 |
Negative | 95 | 76 | ||
P53 | Positive | 58 | 97 | < 0.001 |
Negative | 38 | 12 | ||
NF | Positive | 49 | 43 | 0.023 |
Negative | 10 | 23 | ||