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Table 1 Characteristics of HIV-infected patients newly diagnosed with Kaposi’s sarcoma between 2009 and 2012 in a large community-based primary care network in Kenya

From: Real-world use of chemotherapy for Kaposi’s sarcoma in a large community-based HIV primary care system in Kenya

Characteristic

Median (Interquartile range) or Percentage

(N = 588)

Age, years

35 (30–42)

Male gender

357 (61%)

Documented Symptoms at KS diagnosis

 Weight loss (self-reported)

139 (24%)

 Diarrhea (self-reported)

47 (8%)

 Night sweats

56 (10%)

 Fever (self-reported or measured)

107 (18%)

 ECOG performance status Mean (SD) a

1.34 (0.80)

 ECOG > 1

72 (12%)

Extent of KS on skin

 Localized to one anatomic area

115 (20%)

 More than localized

257 (44%)

 Lymphadenopathy

72 (12%)

 KS Lesions in oral cavity

176 (30%)

 Interfering with swallowing

30 (5.1%)

 GI KS suspected/confirmed

30 (5.1%)

 Pulmonary KS suspected/confirmed

51 (8.7%)

  > 1 Ulcerated KS lesion

69 (12%)

 Edema N

247 (42%)

 Interfering with function

26 (4.4%)

 CD4+ T cells, count/μl b

184 (68–350)

  < 50

71 (12%)

 51–100

48 (8.2%)

 101–200

79 (13%)

 201–350

80 (14%)

  > 350

92 (16%)

Antiretroviral therapy (ART)

 On ART at time of diagnosis

177 (30%)

 Days on ART among patients on ART at time of KS diagnosis

119 (42–539)

 On ART > 60 days prior to KS diagnosis

112 (19%)

Chemotherapy indication

 ACTG T1

333 (57%)

 WHO “Severe KS”

92 (16%)

Education

 None

56 (10%)

 Primary

346 (62%)

 Secondary

135 (24%)

 Tertiary

25 (4.4%)

Travel time to clinic

  < 30 min

132 (23%)

 30–60 min

193 (34%)

 1–2 h

135 (23%)

  > 2 h

115 (20%)

 Water piped into home

74 (13%)

  1. aECOG = Eastern Cooperative Oncology Group performance status
  2. bCD4 count proximal to diagnosis was defined as the closest CD4 count to the date of KS diagnosis within a window from 30 days prior to diagnosis or up to 60 days after the diagnosis date. There was no proximal CD4 count available on 218 of the participants