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Table 3 Genetic association analysis for the ESR1, HER2, UGT1A4, and UGT2B7 SNPs using different genetic models

From: Association between ESR1, ESR2, HER2, UGT1A4, and UGT2B7 polymorphisms and breast Cancer in Jordan: a case-control study

GeneSNP IDCategory TestOdds Ratio95% CIChi square*
ESR1rs2234693Het (GT) vs Common Hz (GG)0.650.41–1.043.31
Rare Hz (TT) vs Het (GT)1.590.99–2.553.7
Rare Hz (TT) vs Common Hz (GG)1.040.6–1.790.02
rs9340799Het (AG) vs Common Hz (AA)0.690.44–1.082.67
Rare Hz (GG) vs Het (AG)1.691.03–2.774.29
Rare Hz (GG) vs Common Hz (AA)1.160.67–2.030.28
rs3020410Het (CT) vs Common Hz (CC)1.210.72–2.040.53
Rare Hz (TT) vs Het (AG)1.260.2–8.010.06
Rare Hz (TT) vs Common Hz (CC)1.520.25–9.230.21
rs3798577Het (GT) vs Common Hz (GG)0.610.4–0.954.88
Rare Hz (TT) vs Het (GT)0.930.57–1.530.07
Rare Hz (TT) vs Common Hz (GG)0.570.33–0.984.16
HER2rs1058808Het (GA) vs Common Hz (GG)1.180.8–1.760.7
Rare Hz (AA) vs Het (GA)0.710.37–1.351.1
Rare Hz (AA) vs Common Hz (GG)0.840.44–1.590.29
UGT1A4rs6755571Het (GA) vs Common Hz (AA)1.270.67–2.390.55
Rare Hz (GG) vs Het (GA)0.40.03–4.70.57
Rare Hz (GG) vs Common Hz (AA)0.50.05–5.590.33
UGT2B7rs28365062Het (CT) vs Common Hz (CC)0.870.57–1.350.37
Rare Hz (TT) vs Het (CT)1.090.38–3.120.03
Rare Hz (TT) vs Common Hz (CC)0.960.35–2.610.01
rs4348159Het (CT) vs Common Hz (CC)0.890.58–1.380.25
Rare Hz (TT) vs Het (CT)1.210.43–3.370.13
Rare Hz (TT) vs Common Hz (CC)1.080.41–2.880.03
  1. * For significant association χ2 should be > 3.84 with P < 0.025
  2. CI indicates confidence interval