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Fig. 4 | BMC Cancer

Fig. 4

From: Bag-1 stimulates Bad phosphorylation through activation of Akt and Raf kinases to mediate cell survival in breast cancer

Fig. 4

Bad phosphorylation at Ser136 and Ser112 increases upon Bag-1 overexpression. a. Immunoblot analysis of total and phosphorylated Bad levels in cell lysates from Bag-1 overexpressing, Bag-1-silenced and untransfected cells. b. Bad expression and phosphorylation profiles in tumor and normal tissues of breast cancer patients with ER + PR + Her2-, ER + PR + Her2+, ER-PR-Her2+ and ER-PR-Her2- subtypes. Expression levels were normalized to vinculin, and t-test was used to evaluate significant changes

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BMC Cancer

ISSN: 1471-2407

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