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Table 3 Univariate and multivariate analysis of overall survival in 236 CRC patients

From: Elevated expression of AGGF1 predicts poor prognosis and promotes the metastasis of colorectal cancer

 

Overall survival

Univariate analysis

Multivariate analysis

HR (95% CI)

p Value

HR (95% CI)

p Value

Age (yr)

0.895 (0.530–1.512)

0.679

  

Gender

1.222 (0.723–2.066)

0.455

  

Tumor location

1.168 (1.000–1.364)

0.050*

1.190 (0.994–1.423)

0.058

T classification

3.182 (1.705–5.937)

< 0.001*

2.938 (1.404–6.149)

0.004*

N classification

2.243 (1.615–3.115)

< 0.001*

0.912 (0.586–1.419)

0.002*

M classification

9.412 (5.481–16.162)

< 0.001*

9.385 (4.907–17.952)

< 0.001*

AJCC stage (III -IV vs I- II)

7.927 (3.394–18.511)

< 0.001*

3.369 (1.147–9.895)

0.027*

Recurrence

3.730 (2.144–6.488)

< 0.001*

5.667 (2.882–11.140)

< 0.001*

Differentiation

0.616 (0.370–1.025)

0.062

  

AGGF1

4.182 (2.384–7.333)

< 0.001*

3.320 (1.814–6.077)

< 0.001*

  1. HR: hazard ratio; CI: confidence interval
  2. * Significant differences