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Table 3 Univariate and multivariate analysis of overall survival in 236 CRC patients

From: Elevated expression of AGGF1 predicts poor prognosis and promotes the metastasis of colorectal cancer

 Overall survival
Univariate analysisMultivariate analysis
HR (95% CI)p ValueHR (95% CI)p Value
Age (yr)0.895 (0.530–1.512)0.679  
Gender1.222 (0.723–2.066)0.455  
Tumor location1.168 (1.000–1.364)0.050*1.190 (0.994–1.423)0.058
T classification3.182 (1.705–5.937)< 0.001*2.938 (1.404–6.149)0.004*
N classification2.243 (1.615–3.115)< 0.001*0.912 (0.586–1.419)0.002*
M classification9.412 (5.481–16.162)< 0.001*9.385 (4.907–17.952)< 0.001*
AJCC stage (III -IV vs I- II)7.927 (3.394–18.511)< 0.001*3.369 (1.147–9.895)0.027*
Recurrence3.730 (2.144–6.488)< 0.001*5.667 (2.882–11.140)< 0.001*
Differentiation0.616 (0.370–1.025)0.062  
AGGF14.182 (2.384–7.333)< 0.001*3.320 (1.814–6.077)< 0.001*
  1. HR: hazard ratio; CI: confidence interval
  2. * Significant differences