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Fig. 5 | BMC Cancer

Fig. 5

From: Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer

Fig. 5

The LMGS up-regulation is associated with poor prognosis in patients with serous ovarian cancer. The LMGS was significantly enriched in a patients undergoing suboptimal cytoreduction and b those with late-stage disease. The prognostic significance of the LMGS in patients with serous ovarian cancer was validated in dataset c TCGA (N = 557), d GSE9891 (N = 240), e GSE26712 (N = 185), f GSE49997 (N = 171). g Survival analysis across the four validation datasets (N = 646) was conducted in patients with late-stage disease undergoing optimal cytoreduction

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BMC Cancer

ISSN: 1471-2407

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