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Table 1 Univariate and multivariate analyses of clinicopathological variables in relation to overall survival in patients undergoing potentially curative resection for gastric cancer

From: Complete blood count-based inflammatory score (CBCS) is a novel prognostic marker for gastric cancer patients after curative resection

Clinicopathological features

Univariate analysis

Multivariate analysis

HR (95% CI)

P

HR (95% CI)

P

Age

1.03 (1.02–1.04)

< 0.001

1.02 (1.01–1.03)

< 0.001

Sex

 

0.979

  

 Male

Reference

   

 Female

1.00 (0.83–1.21)

   

BMI

0.94 (0.92–0.97)

< 0.001

 

0.058

ASA score

 

0.013

 

0.740

 1

Reference

   

 2

1.29 (1.09–1.53)

   

 3

1.18 (0.75–1.86)

   

Tumor location

 

< 0.001

 

< 0.001

 Upper

Reference

 

Reference

 

 Middle

1.05 (0.83–1.33)

 

0.92 (0.72–1.17)

 

 Lower

0.59 (0.48–0.73)

 

0.79 (0.64–0.97)

 

 Mixed

1.56 (1.22–1.98)

 

1.32 (1.03–1.70)

 

Tumor size (cm)

1.02 (1.01–1.02)

< 0.001

1.01 (1.00–1.01)

0.003

Histologic type

 

0.069

  

 Differentiated

Reference

   

 Undifferentiated

1.22 (0.99–1.51)

   

Vascular invasion

 

< 0.001

 

0.655

 Negative

Reference

   

 Positive

1.69 (1.41–2.02)

   

Perineural invasion

 

< 0.001

 

0.885

 Negative

Reference

   

 Positive

1.63 (1.33–1.99)

   

pTNM stage

 

< 0.001

 

< 0.001

 I

Reference

 

Reference

 

 II

2.65 (1.82–3.68)

 

2.00 (1.38–2.90)

 

 III

9.74 (7.05–13.46)

 

6.80 (4.91–9.41)

 

Adjuvant chemotherapy

 

0.260

  

 No

Reference

   

 Yes

1.10 (0.93–1.31)

   

Hb

 

< 0.001

 

0.003

  < 125

Reference

 

Reference

 

  ≥ 125

0.51 (0.43–0.60)

 

0.77 (0.65–0.91)

 

LMR

 

< 0.001

 

0.003

  < 3.4

Reference

 

Reference

 

  ≥ 3.4

0.59 (0.50–0.70)

 

0.78 (0.65–0.91)

 

PLR

 

< 0.001

 

0.434

  < 161.3

Reference

   

  ≥ 161.3

1.70 (1.44–2.00)

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