Fig. 4
From: Mesenchymal stem cells promote glioma neovascularization in vivo by fusing with cancer stem cells
Fusion cells cultured on Matrigel. a-c: fusion cells were inoculated on Matrigel, and the cells showed fusiform or star-shaped protrusions at 6 h (a). After 12 h, some cell protrusions merged to form a short strip-like structure (b). After 24 h, multiple cells were observed to form a circular and tube-like structure (c). BMSCs (d-f) and SU3-RFP cells (g-i) randomly grew in the gel after inoculation, and were disorderly arranged, with no typical lumen structure formation. Scale: a-b, d-i 50 μm, c 100 μm