Table 4 Univariate and multivariate analyses of preoperative prognostic factors for recurrence-free survival and overall survival

 Male

1.70

0.77–3.74

0.19

1.23

0.33–4.64

0.76

 Female

1

1

  < 65

1

1

  ≥ 65

0.95

0.42–2.18

0.91

1.46

0.39–5.49

0.58

  < 5

1.29

0.64–2.58

0.48

1.69

0.45–6.39

0.44

  ≥ 5

1

1

  < 5

1

1

  ≥ 5

1.80

0.93–3.53

0.84

1.16

0.34–3.97

0.81

 T2 and T3

1

1

1

 T4

3.00

1.53–5.91

0.001

2.01

0.92–4.42

0.08

3.24

0.99–10.62

0.05

 Negative

1

1

 Positive

1.35

0.69–2.62

0.38

0.87

0.27–2.85

0.82

 Negative

1

1

 Positive

1.71

0.84–3.48

0.14

1.38

0.37–5.21

0.64

Clinical CRM

 Negative

1

1

1

1

 Positive

2.99

1.54–5.80

0.001

1.97

0.90–4.35

0.09

4.43

1.30–15.14

0.02

3.24

0.90–11.68

0.07

 Negative

1

1

1

1

 Positive

3.37

1.72–6.61

< 0.001

2.74

1.36–5.50

0.005

4.43

1.35–14.51

0.01

3.15

0.91–10.89

0.07

  < 60

3.37

1.53–7.42

0.003

3.48

1.57–7.72

0.002

3.90

0.84–18.06

0.08

  ≥ 60

1

1

1