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Table 4 Positive immunohistochemical profile of esophageal neuroendocrine carcinomas

From: The clinicopathologic features and prognosis of esophageal neuroendocrine carcinomas: a single-center study of 53 resection cases

Antibody

Pure NECs+(%)

MiNECs+(%)

P

Syn+

26/30(86.7)

12/15(80.0)

0.884

CgA+

16/25(64.0)

5/13(38.5)

0.178

CD56

14/16(87.5)

9/11(81.8)

1.000

P63

2/26(3.8)

6/8(75.0)

0.001

CK5/6

1/18(5.6)

6/10(60.0)

0.003

CK8/18

4/5(80)

3/4(75)

0.858

CKpan

13/16(81.3)

3/4(75)

0.784

P40

0/8(0)

2/3(66.7)

0.010

CK7

2/4(50.0)

4/4(100)

0.063

  1. +NECs: neuroendocrine carcinomas; MiNECs: mixed neuroendocrine-nonneuroendocrine carcinomas; Syn: synaptophysin; CgA: chromogranin A