Granulocyte-colony stimulating factor-associated aortitis in a woman with advanced breast cancer: a case report and review of the literature

Table 1 Reported cases of G-CSF-associated aortitis including the present case

References	[10]	[11]		[12]	[13]	[14]	[15]	[16]	[17]	Present case
Year	2018	2019		2009	2017	2018	2004	2016	2009	2019
Age	61	60	70	54	67	47	55	52	28	72
Gender	Female	Female	Female	Male	Female	Female	Female	Male	Male	Female
Primary disease	Breast cancer, Stage IV	Breast cancer	Breast cancer	Lung cancer, Stage III	Lung cancer, advanced	Ovarian cancer, Stage IIIC	Bone marrow donor	Bone marrow donor	Aortitis syndrome	Breast cancer, stage IV
G-CSF	PFG	G-CSF^a	Filgrastim	Filgrastim	PFG	G-CSF^a	Filgrastim	Filgrastim	G-CSF^a	PFG
Period^b	7 - 17	5 - 15	15 - 25	5 - 11	7 - 13	14 – 30^c	2-14	6months	5-	4-14
Location of aortitis	Thoracic	Thoraco-abdominal		Abdominal	Thoracic, issection	Thoracic	Thoraco-abdominal	Abdominal and iliac aneurysms	Thoraco-abdominal and carotid arteritis	Thoracic
Diagnosis modality	CT, US	CT	PET/CT	CT, MRI	CT, US	CT	CT, MRI, US	CT	CT	PET/CT
Steroid treatment	None	PSL 60mg	PSL 60mg	None	mPSL 80mg	PSL 30mg	Corticosteroid1g	PSL 40mg	mPSL 1g	None

G-CSF granulocyte-colony stimulating factor, mPSL methylprednisolone, PFG pegfilgrastim, PSL prednisolone
^aDetails unknown
^bDays with symptoms from G-CSF administration
^cDays from chemotherapy

ISSN: 1471-2407