Skip to main content

Table 2 Correlations between renal function and urinary markers

From: Correlation of prechemotherapy urinary megalin ectodomain (A-megalin) levels with the development of cisplatin-induced nephrotoxicity: a prospective observational study

 eGFRΔeGFR
rPrP
eGFR−0.3950.007
ΔeGFR−0.3950.007
A-megalin0.2990.046−0.4580.002
ΔA-megalin0.2410.111−0.2420.110
C-megalin0.0430.780− 0.2080.171
ΔC-megalin0.0750.623−0.1790.239
NAG−0.2600.864−0.1420.352
ΔNAG−0.0920.546−0.2350.120
α1-MG−0.0650.669−0.2870.056
Δα1-MG−0.0230.8800.2310.126
β2-MG−0.1420.352−0.0480.757
Δβ2-MG−0.2480.100−0.0380.802
NGAL−0.0710.6420.1240.417
L-FABP0.1230.421−0.0740.629
  1. r, Pearson’s correlation coefficient. α1-MG, α1-microglobulin; β2-MG, β2-microglobulin; eGFR, estimated glomerular filtration rate; L-FABP, liver-type fatty acid-binding protein; NAG, N-acetyl-β-D-glucosaminidase; NGAL, neutrophil gelatinase-associated lipocalin. ΔeGFR, maximum change from the baseline value to the lowest value of eGFR during follow-up. Δurinary marker = (maximum urinary marker after cisplatin administration) – (urinary marker before cisplatin administration). NGAL and L-FABP were measured only before cisplatin administration