Skip to main content

Table 2 Correlations between renal function and urinary markers

From: Correlation of prechemotherapy urinary megalin ectodomain (A-megalin) levels with the development of cisplatin-induced nephrotoxicity: a prospective observational study

 

eGFR

ΔeGFR

r

P

r

P

eGFR

–

−0.395

0.007

ΔeGFR

−0.395

0.007

–

A-megalin

0.299

0.046

−0.458

0.002

ΔA-megalin

0.241

0.111

−0.242

0.110

C-megalin

0.043

0.780

− 0.208

0.171

ΔC-megalin

0.075

0.623

−0.179

0.239

NAG

−0.260

0.864

−0.142

0.352

ΔNAG

−0.092

0.546

−0.235

0.120

α1-MG

−0.065

0.669

−0.287

0.056

Δα1-MG

−0.023

0.880

0.231

0.126

β2-MG

−0.142

0.352

−0.048

0.757

Δβ2-MG

−0.248

0.100

−0.038

0.802

NGAL

−0.071

0.642

0.124

0.417

L-FABP

0.123

0.421

−0.074

0.629

  1. r, Pearson’s correlation coefficient. α1-MG, α1-microglobulin; β2-MG, β2-microglobulin; eGFR, estimated glomerular filtration rate; L-FABP, liver-type fatty acid-binding protein; NAG, N-acetyl-β-D-glucosaminidase; NGAL, neutrophil gelatinase-associated lipocalin. ΔeGFR, maximum change from the baseline value to the lowest value of eGFR during follow-up. Δurinary marker = (maximum urinary marker after cisplatin administration) – (urinary marker before cisplatin administration). NGAL and L-FABP were measured only before cisplatin administration