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Table 2 Association between serum uPA and clinical characteristics in 287 HCC patients undergoing curative resection

From: Elevated levels of serum urokinase plasminogen activator predict poor prognosis in hepatocellular carcinoma after resection

 

High uPA (n = 81)

Low uPA (n = 206)

P-value

Age (years)

60.5 ± 12.9

59.2 ± 11.2

0.431

Male gender, n (%)

61 (75.3%)

171 (83.0%)

0.136

Total bilirubin (mg/dl)

0.9 ± 0.7

1.0 ± 2.8

0.804

Albumin (mg/dl)

3.2 ± 0.5

3.5 ± 0.6

< 0.001

Platelet < 150 × 109/L, n (%)

46 (56.8%)

88 (42.7%)

0.032

AFP > 200 ng/mL, n (%)

24 (29.6%)

42 (20.4%)

0.094

Liver cirrhosis, n (%)

48 (59.3%)

75 (36.4%)

< 0.001

Tumor size > 5 cm, n (%)

24 (29.6%)

64 (31.1%)

0.812

Vascular invasion, n (%)

46 (56.8%)

114 (55.3%)

0.824

Pathology stage III + IV, n (%)

19 (23.5%)

34 (16.5%)

0.172

  1. High uPA: uPA ≥1 ng/ml; low uPA: uPA < 1 ng/ml