Table 2 Serum metabolites with p-values from t-tests, fasting group versus carbohydrate (CH), for all patients and for the ER positive subset

Metabolite

p-value^a

Fold change

p-value^a ER+

Fold change ER+

3-Hydroxybutyrate

0.010

-1.06

0.010

-1.07

Acetate

<0.001

-1.22

<0.001

-1.21

Acetoacetate

<0.001

-1.25

<0.001

-1.20

Acetone

0.250

-1.18

0.508

-1.11

Alanine

0.692

1.01

0.544

-1.02

Asparagine

0.237

-1.05

0.376

-1.04

Citrate

0.503

1.03

0.726

1.01

Creatine

0.905

-1.01

0.704

-1.02

Creatinine

0.066

-1.06

0.039

-1.07

Dimethylsulfone

0.319

-1.09

0.154

-1.15

Glucose

0.969

1.00

0.972

1.00

Glutamine

0.005

-1.06

0.013

-1.07

Glycerol

0.065

-1.05

0.054

-1.06

Glycoprotein

0.243

-1.06

0.408

-1.05

Isoleucine

<0.001

-1.26

0.001

-1.22

Isopropyl alcohol

0.009

-1.12

0.038

-1.10

Lactate

<0.001

1.36

<0.001

1.26

Leucine

<0.001

-1.20

0.002

-1.17

Lysine

<0.001

-1.12

<0.001

-1.11

Methanol

0.495

-1.04

0.511

-1.04

Methionine

0.052

-1.11

0.062

-1.11

N-acetylated groups

<0.001

-1.15

<0.001

-1.15

Phenylalanine

<0.001

-1.12

<0.001

-1.13

Proline

0.298

-1.03

0.236

-1.03

Propylene Glycol

<0.001

-1.13

0.004

-1.10

Pyruvate

<0.001

1.27

<0.001

1.23

Threonine

0.035

-1.07

0.016

-1.08

Valine

<0.001

-1.31

<0.001

-1.29