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Table 2 Toxicities of DEB-TACE group and cTACE group

From: Conventional versus drug-eluting beads chemoembolization for infiltrative hepatocellular carcinoma: a comparison of efficacy and safety

Variables

DEB-TACE (n = 56)

cTACE (n = 33)

P value

Clinical toxicity (grade 1–2)

 Abdominal pain (yes/no)

38/18, 67.9%

29/4, 87.9%

0.034

 Fever (yes/no)

22/34, 39.3%

21/12, 63.6%

0.026

 Nausea (yes/no)

3/53, 5.4%

6/27, 18.2%

0.072

 Diarrhea (yes/no)

3/53, 5.4%

4/29, 12.1%

0.416

Clinical toxicity (grade 3–4)

 Hepatic failure (yes/no)

2/54, 3.6%

2/31, 6.1%

0.625

 Death (yes/no)

0

0

N/A

 GI bleeding (yes/no)

1/55, 1.8%

1/32, 3.0%

1.000

Laboratory toxicity (grade 1–2)

 Elevated ALT (yes/no)

12/44, 21.4%

9/24, 27.3%

0.531

 Elevated AST (yes/no)

5/51, 8.9%

8/25, 24.2%

0.064

 Elevated ALP (yes/no)

10/46, 17.9%

6/27, 18.2%

0.969

 Hyperbilirubinemia (yes/no)

17/39, 30.4%

9/24, 27.3%

0.757

 Creatinine (yes/no)

0

0

N/A

Laboratory toxicity (grade 3–4)

 Elevated ALT (yes/no)

0

0

N/A

 Elevated AST (yes/no)

0

0

N/A

 Elevated ALP (yes/no)

0

0

N/A

 Hyperbilirubinemia (yes/no)

1/55, 1.8%

3/30, 9.1%

0.142

 Creatinine (yes/no)

0

0

N/A

  1. Note: DEB-TACE Drug-eluting beads transarterial chemoembolization, cTACE conventional transarterial chemoembolization, ALT Alanine aminotransferase, AST Aspartate aminotransferase, ALP Alkaline phosphatase, GI Gastrointestinal