Fig. 5
Growth rate for eight cell lines and correlation between growth rate and IC50. a Table shows the estimated growth rate and doubling time for Luminal cells (MCF7 and HCC1428), HER2 subtype (HCC1419 and HCC202), and TNBC subtype (MDA453, MDA231, SUM149, and BT549). Cellular doubling time was determined by evaluation of the time that it takes for a cell population to double during the log-phase phase (i.e., during linear growth). b Graphical depiction of cellular proliferation over time. The number of cells measured at each time point (x-axis) is specified at the y -axis. c Graphical depiction of the correlation between IC50 and growth rate (k). Yellow dots - Luminal cell lines; blue dots - HER2 cell lines; orange dots - TNBC cell liness