Table 2 Univariate and multivariate analyses for progression-free and overall survival

HR (95% CI)

p

HR (95% CI)

p

HR (95% CI)

p

HR (95% CI)

p

Age > 65 y

1.007 (0.983–1.032)

0.584

1.001 (0.960–1.004)

0.968

ECOG PS > 1

4.441 (1.948–10.127)

< 0.001

3.544 (1.413–8.889)

0.005

3.390 (1.161–9.898)

0.026

Visceral metastasis†

1.410 (0.723–2.752)

0.314

3.473 (0.785–15.386)

0.101

Triple-negative

(ER/PR/HER2)

4.463 (1.900–10.483)

0.001

3.329 (1.328–8.342)

0.010

3.995 (1.177–13.296)

0.026

CTCs > 32/ml

1.003(1.000–1.006)

0.089

1.006 (1.003–1.010)

< 0.001

7.266 (1.775–29.741)

0.006

cCSC > 15%

2.903 (1.563–5.392)

0.001

2.867 (1.338–6.140)

< 0.0001

8.236 (2.269–29.894)

0.001

16.238 (3.167–83.264)

0.001