Table 1 Characteristics for UTUC patients stratified by lymph node dissection
Characteristic | Totala | No LNDa | LNDa | P valueb |
|---|---|---|---|---|
No. (%) | No. (%) | No. (%) | ||
Total | 7278 (100) | 5317 (73.1) | 1961 (26.9) | |
Age (years) c | < 0.001 | |||
Mean ± SD | 71.9 ± 10.8 | 72.4 ± 10.8 | 70.7 ± 10.6 | |
Median | 73 | 74 | 72 | |
Range | 22–101 | 22–101 | 34–96 | |
Gender | 0.904 | |||
Male | 4295 (59.0) | 3140 (43.1) | 1155 (15.9) | |
Female | 2983 (41.0) | 2177 (29.9) | 806 (11.1) | |
Race | < 0.001 | |||
White | 6419 (88.2) | 4744 (65.2) | 1675 (23.0) | |
Other | 859 (11.8) | 573 (7.9) | 286 (3.9) | |
Marital status | 0.284 | |||
Married | 4421 (60.7) | 3205 (44.0) | 1216 (16.7) | |
Unmarried | 2588 (35.6) | 1919 (26.4) | 669 (9.2) | |
Unknown | 269 (3.7) | 193 (2.7) | 76 (1.0) | |
Primary site | 0.574 | |||
Renal pelvis | 5032 (69.1) | 3686 (50.6) | 1346 (18.5) | |
Ureter | 2246 (30.9) | 1631 (22.4) | 615 (8.5) | |
Laterality | < 0.001 | |||
Left | 3665 (50.4) | 2576 (35.4) | 1089 (15.0) | |
Right | 3607 (49.6) | 2736 (37.6) | 871 (12.0) | |
Paired | 6 (< 1%) | 5 (< 1%) | 1 (< 1%) | |
Tumor size | < 0.001 | |||
≤ 2 cm | 1178 (16.2) | 899 (12.4) | 279 (3.8) | |
> 2 cm | 5357 (73.6) | 3833 (52.7) | 1524 (20.9) | |
Unknown | 743 (10.2) | 585 (8.0) | 158 (2.2) | |
Grade | < 0.001 | |||
I | 292 (4.0) | 249 (3.4) | 43 (0.6) | |
II | 1102 (15.1) | 922 (12.7) | 180 (2.5) | |
III | 2096 (28.8) | 1492 (20.5) | 604 (8.3) | |
IV | 3788 (52.0) | 2654 (36.5) | 1134 (15.6) | |
T stage | < 0.001 | |||
T1 | 2279 (31.3) | 1854 (25.5) | 425 (5.8) | |
T2 | 1353 (18.6) | 1038 (14.3) | 315 (4.3) | |
T3 | 3075 (42.3) | 2116 (29.1) | 959 (13.2) | |
T4 | 571 (7.8) | 309 (4.2) | 262 (3.6) | |
Lymph node status status | – | |||
pNx | 5317 (73.1) | 5317 (73.1) | – | |
pN0 | 1296 (17.8) | – | 1296 (17.8) | |
pN1–3 | 665 (9.1) | – | 665 (9.1) | |
Chemotherapy | < 0.001 | |||
No/Unknown | 6020 (82.7) | 4635 (63.7) | 1385 (19.0) | |
Yes | 1258 (17.3) | 682 (9.4) | 576 (7.9) | |
Year of surgery | ||||
2004–2007 | 2424 (33.3) | 1865 (25.6) | 559 (7.7) | < 0.001 |
2008–2011 | 2451 (33.7) | 1803 (24.8) | 648 (8.9) | |
2012–2015 | 2403 (33.0) | 1649 (22.7) | 754 (10.4) | |