Table 1 Characteristics of patients and transplantation
Patients n = 56 (100%) | |
|---|---|
Immunophenotype | |
B ALL | 31 (55%) |
T ALL | 25 (45%) |
1 CR | 26 (46%) |
> 2 CR | 30 (54%) |
Median age at transplant (range) years | 9,04 (1,72–17) |
Patient gender | |
Male | 38 (68%) |
Female | 18 (32%) |
Donor type | |
Matched related | 25 (45%) |
Matched unrelated | 28 (50%) |
Mismatched related | 3 (5%) |
Donor gender | |
Male | 31 (55%) |
Female | 25 (45%) |
Stem cell source | |
Bone marrow | 47 (84%) |
Peripheral blood | 9 (16%) |
Conditioning regimen | |
Radiation-base | 41 (73%) |
Busulfan-based | 2 (3%) |
Reduced toxicity | 13 (24%) |
Serotherapy (ATG) | |
YES | 28 (50%) |
NO | 28 (50%) |
Number of CD34+ cells (median 4,47) range (2–13,3 × 106/kg) | |
< 4,47 × 106 | 35 (62%) |
> 4,47 × 106 | 21 (38%) |
aGvHD | 23 (41%) |
cGvHD | 4 (7%) |