Table 1 Relationship between molecular profiles and the pathologic factors
Grade 1,2/3,4 | p value | pT1,2/3,4 | p value | pN0/1,2 | p value | |
|---|---|---|---|---|---|---|
(n = 14/36) | (n = 13/37) | (n = 32/18) | ||||
Mutation (+) of Nrf2 (n = 5) | 1 / 4 | 0.7471 | 0 / 5 | 0.1624 | 3 / 2 | 0.9687 |
No mutation of Nrf2 (n = 45) | 13 / 32 | 13 / 32 | 29 / 16 | |||
C/C at rs6721961 (n = 30) | 8 / 22 | 0.7975 | 8 / 22 | 0.8953 | 19 / 11 | 0.4915 |
C/A or A/A at rs6721961 (n = 20) | 6 / 14 | 5 / 15 | 13 / 7 | |||
Nrf2 Low (n = 26) | 8 / 18 | 0.6499 | 10 / 16 | 0.0365 | 19 / 7 | 0.1988 |
Nrf2 High (n = 24) | 6 / 18 | 3 / 21 | 13 / 11 | |||
Mutation (+) of Keap1 (n = 11) | 1 / 10 | 0.1477 | 1 / 10 | 0.1477 | 6 / 5 | 0.2928 |
No mutation of Keap1 (n = 39) | 13 / 36 | 12 / 27 | 26 / 13 |