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Table 2 HIF1A rs2057482 polymorphism genotype distribution and allele frequency in cases and controls

From: The association between hypoxia inducible factor 1 subunit alpha gene rs2057482 polymorphism and cancer risk: a meta-analysis

 

Genotype(N)

Allele frequency (N)

HWE

Score

Case

Control

Case

Control

 

Total

CC

CT

TT

Total

CC

CT

TT

C

T

C

T

Lee 2008 (12)

1150

691

415

44

1048

611

396

41

1797

503

1618

478

0.018

11

Qin 2011 (13)

620

388

196

36

623

393

201

29

972

268

987

259

0.613

12

Li 2012 (14)

662

418

212

32

716

428

241

47

1048

276

1097

335

0.103

12

Wang 2016 (15)

410

301

69

40

490

302

154

34

671

149

758

222

0.022

10

Yamamoto 2016 (16)

462

302

138

22

379

244

121

14

742

182

609

149

0.834

11

Gregory 2016 (17)

180

125

49

6

528

369

147

12

299

61

885

171

0.554

11

Martina 2018 (18)

275

225

47

3

219

176

39

4

497

53

391

47

0.297

10

  1. HWE: Hardy-Weinberg equilibrium