Molecular subtyping improves prognostication of Stage 2 colorectal cancer

BMC Cancer

Table 2 Histological characteristics of colorectal cancer tumours by post-operative stage and by Consensus Molecular Subtype

	Poorly diff %	Mucinous %	LVI %	EMVI %	PNI %
TNM1	11.4	7.5	11.3	0	0
TNM2	18	12.5	23.4	7	9.4
TNM3	18.1	9.5	46.7	26.7	18.1
TNM4	22.7	9.1	72.7	40.9	31.8
P-value	0.5737	0.7864	< 0.001	< 0.001	< 0.001
CMS1	48.3	20	31.7	13.3	8.3
CMS2	9	2.8	28.8	15.2	11.7
CMS3	10.5	18.4	31.6	7.9	7.9
CMS4	17.6	11.8	35.3	23.5	23.5
P-value*	< 0.001	0.0001	0.8686	0.4497	0.3334

Histological characteristics of colorectal cancer tumours by tumour-node-metastasis (TNM) stage and by Consensus Molecular Subtype (CMS) given as percentages. P-value* is derived from analysis of classified tumours only and a P-value of < 0.05 is considered significant. Poorly diff Poorly differentiated, LVI Lymphovascular invasion, EMVI Extramural venous invasion, PNI Perineural invasion

ISSN: 1471-2407